HS-13-PF 17 Determinant of Cervical Carcinoma Incidence Among The Participants of Cervical Cancer Preventive “See And Treat” with Visual Inspection Method of Acid Acetate Taruli Rohana Sinaga Public Health Department Institute of Health Science Mutiara Indonesia Medan, Indonesia Taruli71@yahoo.co.id Abstract! Background: Cervical cancer (neck of the womb) is an important health issue and the leading cause of cancer- related death in women in developing countries. This is a the third type of most common cancer in women, with more than 1.4 million occurrence worldwide. More than 460,000 cases and 80% of them occur in developing countries and about 231,000 women die every year. According to The Ministry of Health Republic of Indonesia (2000), cervical cancer incidence were 100 per 100 thousand people per year. The purpose of this study is to investigate the determinants of the incidence of cervical carcinoma amongst the participants of cervical cancer prevention program with "see and treat" IVA examination method, and assessed the determinants affected its incidence. This study is an observational study using secondary data, derived from Female Cancer Programme, MFS "See and Treat" Project Leiden University Medical Center Leiden, The Netherlands collaborates with eight universities in Indonesia, collected by cross-sectional design. The sequence analysis of data includes univariate, bivariate and multivariate analysis. The results of study revealed that the most dominant major variables affecting the incidence of cervical carcinoma was vaginal fluids where the value of p = 0.000 OR = 4.17 (95% CI :2,61-6, 65). Interaction variables associated with the occurrence of cervical carcinoma was abnormal vaginal discharge (excessively, smelling and yellow) with the age of first marriage p = 0.003, OR = 0.88 (95% CI :0,34-2, 23). Guidance and counseling should be socialized concerning the main determinants associated with the incidence of cervical carcinoma through the media effectively and efficiently to encourage the women for regularly check-up. Keywords; cervical carsinoma, cervical cancer I. INTRODUCTION In Indonesia, the cancer incidence data still unknown. Estimated, 90-100 new cases per 100,000 population per year, or approximately 180,000 new cases per year, and the gynecologic cancer constitute the greatest number, while ! them were cervical cancer. From 1986 to 1990, The RSCM Hospital found 1821 patients with cervical cancer among 2360 cases of gynecologic cancers [1], while The Ministry of Health Republic of Indonesia (2000) estimated 100 incidences per 100 thousand inhabitants per year. II. METHOD This study is an observational study using secondary data derived from Female Cancer Programme, MFS “See and Treat” Project Leiden University Medical Center Leiden, The Netherlands with eight universities in Indonesia and those collected by the cross-sectional design. The research was carried out after an cervical carcinoma incident examination with visual inspection method of acid acetate, to capture the characteristics of cervical cancer among the participants of Indonesian “see and treat” model in cervical cancer prevention program with visual inspection method of acid acetate. Population is the total units of analysis to be investigated [2]. The population of study were all participants of regional “see and treat” model cervical cancer prevention program in Medan from December 2007 to July 2008 who attend the cervical carcinoma examination with acetic acid visual inspection methods, and has the registered variables study, both dependent and independent (complete samples frame). Sample is part of units in population to be investigated. The results are expected describe the actual characteristics in population [2]. The sample of study is total sampling or overall cervical carcinoma prevention program selected randomly by Indonesian "See and Treat" model, team in North Sumatra regional location from December 2007 to July 2008. The minimum sample was calculated by two-test sample size with two-tailed hypothesis formula [3], [8], as follows: