Kareem Shati et al (2020): Effect of Anethum Gravelens extract on lipid metabolism Oct 2020 Vol. 23 Issue 16 Annals of Tropical Medicine & Public Health http://doi.org/10.36295/ASRO.2020.231601 Studying the effect of Anethum Graveolens extract on parameters of lipid metabolism in white rat males Zahraa Reasan Kareem Shati 1 , Ali R Mulakhudair 2 and Muna. N. Khalaf 3 1 Department of Food Science and Technology, College of Food Sciences, Al-Qasim green University, Iraq. ZahraaReasan@fosci.uoqasim.edu.iq 2 Department of Food Health and Nutrition, College of Food Sciences, Al-Qasim green University, Iraq. Armulakhudair1@fosci.uoqasim.edu.iq 3 Department of Food Science and Technology, College of Food Sciences, Al-Qasim green University, Iraq. MunaNajmKhalaf@fosci.uoqasim.edu.iq Abstract: This study was taken place in the animal house of Al- Nahrain University. It studies the effect of Anethum Graveolens plant extract on cholesterol and lipid profile of the animals experiment. The results show that using of alcoholic extract of Anethum Graveolens leads to a reduction in triglycerides, cholesterol, LDL and VLDL levels in comparison with control group. The concentration of triglycerides in control group was 39.21 mg/ 100 ml, while the concentrations of triglycerides in the treated group were 31.88 mg/ 100 ml and 32.6 mg/ 100 ml, for 0.5 ml and 1 ml of treated groups respectively. On the other hand, cholesterol concentration was also tested and its concentration was found to be 88 mg/ 100 ml and 92.2 mg/ 100 ml for the 1 ml and 0.5 ml treated groups respectively in comparison with the control group, which recorded 112.40 mg/ 100 ml. The results also indicate a reduction in the total cholesterol level comparing with control group, which shows low level of good cholesterol HDL 48.7 mg/ 100 ml. On contrary, the treated groups exhibit a high level of HDL, 59 mg/ 100 ml and 56.46 mg/ 100 ml in 1 ml and 0.5 ml treated groups respectively., Further, the concentration of bad cholesterol LDL dropped into 29.37 mg/ 100 ml and 22.48 mg/ 100 ml in 1 ml and 0.5 ml treated groups in comparison to the control group, which was 55.86 mg/ 100 ml,. Regarding VLDL levels, the control group recorded 7.84 ml/ 100 ml, while were 6.37 mg/ 100 ml and 6.52 mg/ 100 ml for both treatments of 0.5 ml and 1 ml respectively. Keywords: Anethum Graveolens, lipid metabolism, white rat males How to cite this article: Kareem Shati ZR, Mulakhudair AR, Khalaf MN (2020): Studying the effect of Anethum Graveolens extract on parameters of lipid metabolism in white rat males, Ann Trop Med & Public Health; 23(S16): SP231601. DOI: http://doi.org/10.36295/ASRO.2020.231601 Introduction: Hyperlipidemia is a dangerous cardiac disease that causes increasing rate of death around the world and it is associated with arteriosclerosis disease. These diseases are mainly caused by increasing in cholesterol level in plasma (1). The increasing of a special kind of fatty proteins related to the increasing of having the first arteriosclerosis disease LDL which has a high ratio of hyperlipidemia, so that it is the cause of having