Accepted Manuscript 2-Pyridyl thiazoles as novel anti-T. cruzi agents: Structural design, synthesis and Pharmacological evaluation Marcos Veríssimo de Oliveira Cardoso, Lucianna Rabelo Pessoa de Siqueira, Elany Barbosa da Silva, Lívia Bandeira Costa, Marcelo Zaldini Hernandes, Marcelo Montenegro Rabello, Rafaela Salgado Ferreira, Luana Faria da Cruz, Diogo Rodrigo Magalhães Moreira, Valéria Rêgo Alves Pereira, Maria Carolina Accioly Brelaz de Castro, Paul V. Bernhardt, Ana Cristina Lima Leite PII: S0223-5234(14)00739-9 DOI: 10.1016/j.ejmech.2014.08.012 Reference: EJMECH 7245 To appear in: European Journal of Medicinal Chemistry Received Date: 17 April 2014 Revised Date: 1 August 2014 Accepted Date: 5 August 2014 Please cite this article as: M.V. de Oliveira Cardoso, L.R.P. de Siqueira, E.B. da Silva, L.B. Costa, M.Z. Hernandes, M.M. Rabello, R.S. Ferreira, L.F. da Cruz, D.R. Magalhães Moreira, V.R.A. Pereira, M.C.A.B. de Castro, P.V. Bernhardt, A.C.L. Leite, 2-Pyridyl thiazoles as novel anti-T. cruzi agents: Structural design, synthesis and Pharmacological evaluation, European Journal of Medicinal Chemistry (2014), doi: 10.1016/j.ejmech.2014.08.012. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.