DOI: 10.21276/aimdr.2017.3.6.EN2 Case Report ISSN (O):2395-2822; ISSN (P):2395-2814 Annals of International Medical and Dental Research, Vol (3), Issue (6) Page 4 Section: Ear, Nose & Throat Sjogren’s syndrome variant: A Case Report Shweta Sharma 1 , B B Sharma 2 1 Senior Resident, Department of ENT & Head & Neck Surgery , SGT Medical College Budhera (Gurgaon) 122505. 2 Professor & HOD, Dept.of Radio-diagnosis,SGT Medical College Budhera (Gurgaon) 122505. Received: August 2017 Accepted: September 2017 Copyright: © the author(s), publisher. Annals of International Medical and Dental Research (AIMDR) is an Official Publication of “Society for Health Care & Research Development”. It is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non- commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT Sjogren’s syndrome is a part of the disease where moisture producing glands are affected by auto immune disease. There is variety of symptomatology depending upon the type and extent of the involvement of the underlying glands. There is dryness of the mouth when salivary glands are involved and dryness of the eyes when lachrymal glands are affected. We present 43-years old female who had subclinical and confusing symptomsof swelling and dryness of mouth. The radiological evaluation by ultrasound (US),non contrast computerized tomography (NCCT), contrast enhanced computerized tomography (CECT ) and magnetic resonance imaging (MRI) studies clinched the diagnosis along with the background of clinical spectrum. Keywords: Sjogren’s syndrome; autoimmune; salivary gland ; ultrasound ;CECT;MRI. INTRODUCTION Sjogren’s syndrome was named after Hernik Sjogren, a Swedish ophthalmologist in 1933. He first time introduced the term of keratoconjunctivitis sicca. This syndrome affects the production of tears and saliva.0.2-1.2% population is affected by this syndrome and the intensity and pattern may vary from person to person. There is predilection for the females with 9:1 as female male ratio. [1] There is always risk of lymphoma in 5 % of affected cases. [2] CASE REPORT 43-years old lady reported with the complaints of mild swelling of both the parotid gland region for the last three years. This swelling was off and on appearing with dull pain. Now for the last three months she was complaining of dryness of mouth. She had taken medication for symptomatic complaints which were subsiding and appearing again. On examination she was averagely built with normal physical parameters as per her age.Sytemic examination was non contributory except mild enlargement of both the parotid regions [Figure 1 a,b and c]. Biochemical investigations were within normal limits. HIV status was negative. Ultrasound Name & Address of Corresponding Author B B SHARMA Professor & HOD, Department of Radio-diagnosis, SGT Medical College Budhera (Gurgaon) 122505 C 35 First Floor, Anand Niketan, New Delhi - 110021 examination had revealed bilateral multiple cystic anechoic areas within the parenchyma of parotid glands. No calcification or increased vascularity was noticed in the glands [Figure 2]. The patient was subjected to plain as well as contrast enhanced computerized tomography (CECT) of the face and neck regions. There were multiple well defined hypodense areas seen in both the glands involving superficial as well as deep lobes. Submandibular glands were not appreciated properly [Figure 3a and b], CECT had shown these hypodense areas as non enhancing areas as not part of the glandular parenchyma [Figure 4] Figure 1: Photograph of 43-years old female having bilateral parotid swellings.(a) front view depicting both parotid regions (black arrows ). (b) left side view of left parotid swelling (white vertical hollow arrow) (c) right side view of parotid region (horizontal arrow)