Received: 13 October 2021 Revised: 24 December 2021 Accepted: 2 January 2022 DOI: 10.1002/pbc.29568 Pediatric Blood & Cancer The American Society of Pediatric Hematology/Oncology GLOBAL ONCOLOGY: RESEARCH ARTICLE Global Neuroblastoma Network: An international multidisciplinary neuroblastoma tumor board for resource-limited countries Katherine K. Matthay 1 Jennifer Hylton 2 Neela Penumarthy 3 Mohammed Khattab 4 Shui Yen Soh 5 Hoa Thi Kim Nguyen 6 Ana Patricia Alcasabas 7 Mohammed Fawzy 8 Raya Saab 9 Muhammad Saghir Khan 10 Khalil Ghandour 11 Guillermo Chantada 12 Nehal S. Parikh 13 Lawrence Faulkner 14 Catherine G. Lam 15 Scott C. Howard 16 1 Department of Pediatrics, Benioff Children’s Hospital and University of California San Francisco School of Medicine, San Francisco, California, USA 2 Department of Network Development, Resonance Health, Memphis, Tennessee, USA 3 Department of Pediatrics, Kaiser Permanente, Oakland, California, USA 4 Pediatric Hematology-Oncology Center, Children’s Hospital, University Mohammed Vth, Rabat, Morocco 5 Pediatric Hematology-Oncology, KK Women and Children’s Hospital, Singapore 6 Hue Pediatric Center, Hue Central Hospital, Hue City, Vietnam 7 Division of Pediatric Hematology Oncology, University of the Philippines - Philippine General Hospital, Manila, Philippines 8 Children’s Cancer Hospital - Egypt (CCHE/57357) and National Cancer Institute, Cairo University, Cairo, Egypt 9 Children’s Cancer Institute, Department of Pediatrics, American University of Beirut Medical Center, Beirut, Lebanon 10 Department of Pediatrics, King Faisal Specialist Hospital and Research Center Al Madinah, Riyadh, Saudi Arabia 11 Pediatric Surgery, King Hussein Hospital, Amman, Jordan 12 Fundacion Perez-Scremini-Hospital Pereira Rossell, Montevideo, Uruguay and Institute for Translational Research (IIMT) CONICET-Austral University, Pilar, Argentina 13 Department of Pediatrics, Children’s Hospital of NJ and Rutgers, New Jersey Medical School, Newark, New Jersey, USA 14 Cure2Children Foundation, Florence, Italy 15 Departments of Global Pediatric Medicine and Oncology, St. Jude Children’s Research Hospital, Memphis, Tennessee, USA 16 Acute and Tertiary Care, University of Tennessee Health Science Center College of Medicine Memphis, Memphis, Tennessee, USA Correspondence Katherine K. Matthay, Benioff Children’s Hos- pital and Department of Pediatrics, University of California San Francisco School of Medicine, 550 16th St, San Francisco, CA 94158, USA. Email: kate.matthay@ucsf.edu Funding information UCSF Neuroblastoma Research Fund; Cure2Children Foundation; Resonance Health; Fondazione Umberto Veronesi; St. Jude Chil- dren.s Research Hospital Abstract Background: Tumor boards are part of standard care of patients with complex cancers, but appropriate multidisciplinary expertise and infrastructure are often not available in low- and middle-income countries (LMIC) for pediatric cancers, such as neuroblastoma. Our goal was to review results of a Global Neuroblastoma Network (GNN) tumor board accessible to LMIC. Methods: De-identified clinical cases presented via internet conference during a weekly GNN virtual tumor board from 2010 through 2020 were evaluated in a Abbreviations: ASCT, autologous stem cell transplant; CT, computerized tomography; FDG-PET, fluorodeoxyglucose positron emission tomography; GNN, Global Neuroblastoma Network; HIC, high-income countries; INPC, International Neuroblastoma Pathology Classification; INRG, International Neuroblastoma Risk Group staging system; INSS, International Neuroblastoma Staging System; LDH, lactic dehydrogenase; LMIC, low- and middle-income countries; MIBG, metaiodobenzylguanidine; MRI, magnetic resonance imaging. Pediatr Blood Cancer. 2022;e29568. © 2022 Wiley Periodicals LLC 1 of 10 wileyonlinelibrary.com/journal/pbc https://doi.org/10.1002/pbc.29568