402 Copyright © 2018, IGI Global. Copying or distributing in print or electronic forms without written permission of IGI Global is prohibited. Chapter 18 DOI: 10.4018/978-1-5225-5191-1.ch018 ABSTRACT In the future generation, computer science plays prominent role in the scientifc research. The develop- ment in the feld of computers will leads to the research benefts of scientifc community for sharing data, service computing, building the frameworks and many more. E-Science is the active extending feld in the world by the increase data and tools. The proposed work discusses the use of semantic web applications for identifying the components in the development of scientifc workfows. The main ob- jective of the proposed work is to develop the framework which assists the scientifc community to test and deploy the scientifc experiments with the help of ontologies, service repositories, web services and scientifc workfows. The framework which aims to sustenance the scientifc results and management of applications related to the specifc domain. The overall goal of this research is to automate the use of semantic web services, generate the workfows, manage the search services, manage the ontologies by considering the web service composition. Semantic Web-Based Framework for Scientifc Workfows in E-Science Singanamalla Vijayakumar VIT University, India Nagaraju Dasari VIT University, India Bharath Bhushan VIT University, India Rajasekhar Reddy VIT University, India