522 Pancreatitis in Children: A Single Center Experience Çocuklarda Pankreatit: Tek Merkez Deneyimi Aysegul BUKULMEZ 1 , Pelin BALIKOGLU 1 , Ayse Tolunay OFLU 1 , Cigdem OZER GOKASLAN 2 1 Afyonkarahisar Health Sciences University, Faculty of Medicine, Department of Pediatrics, Afyonkarahisar,Turkey 2 Afyonkarahisar Health Sciences University, Faculty of Medicine, Radiology, Afyonkarahisar, Turkey Correspondence Address / Yazışma Adresi: Ayşegul BUKULMEZ Afyonkarahisar Health Sciences University, Faculty of Medicine, Department of Pediatrics , Afyonkarahisar, Turkey E-posta: aysegulbukulmez@yahoo.com Original Article Özgün Araştırma ABSTRACT Objective: The aim of this study was to evaluate the clinical, laboratory and etiological diferences between children having acute pancreatitis, acute recurrent pancreatitis and chronic pancreatitis. Material and Methods: Medical records of children who were diagnosed with pancreatitis between January 2014 and December 2017 were evaluated retrospectively. The study was approved by the Ethics Committee of Afyonkarahisar University of Health Sciences. Our cases were classifed as acute pancreatitis, acute recurrent pancreatitis and chronic pancretitis according to INSPPIRE group defnitions. Results: Etiology, demographic characteristics, laboratory and radiological fndings were compared between acute pancreatitis (group 1) and acute recurrent and chronic pancreatitis (group 2) groups. 43 patients (78.2%) were enrolled in acute pancreatitis group (group 1). In group 2; 8 cases had acute recurrent pancreatitis and 4 cases had chronic pancreatitis [a total of 12 cases (21.8%)]. When the etiologies of our cases were examined; Group 1 had idiopathic (88.5%), stone (2.3%), trauma (2.3%), infections (4.6%) and choledochal cyst (2.3%), respectively. In group 2, they were found to be idiopathic (50%), congenital anomalies of the pancreatic duct (8.3%), allergy (8.3%), autoimmunity (8.3%) and genetic causes (25%). There was no statistical diference between the groups in terms of laboratory values. In our study, the cause of pancreatitis could not be generally identifed in all groups. Conclusion: In cases having acute pancreatitis, infections were the second most common etiology; and common causes of acute recurrent and chronic pancreatitis have been found as genetic causes. Key Words: Acute pancreatitis, Chronic pancreatitis, Etiology ÖZ Amaç: Bu çalışmada akut pankreatit, akut rekürren pankreatit ve kronik pankreatit tanısı ile izlenen çocukların klinik, laboratuvar ve etiyolojik farklılıklarının değerlendirilmesi amaçlanmıştır. Gereç ve Yöntemler: Ocak 2014-Aralık 2017 tarihleri arasında pankreatit tanısı ile izlenen çocukların tıbbi kayıtları retrospektif olarak değerlendirilmiştir. Çalışmamıza Afyonkarahisar Sağlık Bilimleri Üniversitesi Tıp Fakültesi Etik Kurulu’ndan onay alınmıştır. Olgularımız INSPPIRE grubu tanımlamalarına göre akut pankreatit, akut rekürren pankreatit ve kronik pankretit olarak sınıfandırılmıştır. Akut pankreatit (grup 1) ve akut rekürren ve kronik pankreatit (grup 2) grupları arasında etiyoloji, demografk özellikler, laboratuvar ve radyolojik bulgular karşılaştırılmıştır. Received / Geliş tarihi : 01.08.2019 Accepted / Kabul tarihi : 04.11.2019 Online published : 24.03.2020 Elektronik yayın tarihi DOI: 10.12956/tchd.600267 Turkish Journal of Pediatric Disease Türkiye Çocuk Hastalıkları Dergisi Çıkar Çatışması / Confict of Interest: Tüm yazarlar adına, sorumlu yazar çıkar çatışması olmadığını belirtir. Etik Kurul Onayı / Ethics Committee Approval: Bu çalışmada ulusal ve uluslararası etik kurallara uyulmuştur. The study was approved by Ethics Committee of Afyonkarahisar University of Health Sciences. Yazarların katkısı / Contribution of the Authors: BUKULMAZ A: Constructing the hypothesis or idea of research and/or article,Taking responsibility in the writing of the whole or important parts of the study. BALIKOGLU P: Constructing the hypothesis or idea of research and/or article, Taking responsibility in the writing of the whole or important parts of the study. OFLU AT: Constructing the hypothesis or idea of research and/or article, Taking responsibility in the writing of the whole or important parts of the study. OZER GOKASLAN C: Constructing the hypothesis or idea of research and/or article, Taking responsibility in the writing of the whole or important parts of the study. Atıf yazım şekli / How to cite : Bukulmez A, Balikoglu P, Ofu AT, Ozer Gokaslan C. Pancreatitis in Children: A Single Center Experience. Türkiye Çocuk Hast Derg 2020;14:522-527. BUKULMEZ A : 0000-0002-6013-5172 BALIKOGLU P : 0000-0002-0568-9965 OFLU AT : 0000-0002-5389-2220 OZER GOKASLAN C : 0000-0001-5345-1735