International Journal of Science, Technology & Management www.ijstm.com Volume No.04, Issue No. 05, May 2015 ISSN (online): 2394-1537 122 | Page ANTIMICOBIAL ACTIVITY OF AQUEOUS AND METHANOLIC LEAF AND BARK EXTRACT OF AEGICERAS CORNICULATUM L Pritinanda Mohanty 1 , Suman Jagatee 2 , Santilata Sahoo 3 1 Laboratory of Biochemistry, 2 Molecular Biology, 3 P.G. Department of Botany, UtkalUniversity, Vani Vihar,Bhubaneswar,Odisha,(India) ABSTRACT The study investigated antimicrobial potential of aqueous and methanolic plant extract (leaf and bark) of Aegicerascorniculatum L. (Myrsinaceae) found in the Bhitarkanika delta regions of Odisha State, India. Organic methanolic solvent extracts obtained from different tissues of these plants were investigated by disc diffusion method against six bacterial species Salmonellaparatyphi(MTCC 3220), salmonella typhi,(MTCC 733), Shigellaflexineri (MTCC1457), Valsa sp. (MTCC 82117), Micrococcus luteus (MTCC2470), staphylococcus aureus (MTCC 9011) and one fungal species Candida albicans ( MTCC854 ). Results suggested that both leaf and barkextracts showed antimicrobial activity against the above species. The methanollic extract of dead bark showed more inhibitory effect than living bark and leaf extracts against bacterial species (Shigellaflexineri), fungal species(Candida albicans)followed by staphylococcus aureus, micrococcusluteus,valsa sp., salmonella typhi, and salmonella paratyphi. The growth-inhibitory effect on Shigellaflexineriis more prominent than all other bacterial species (Salmonellaparatyphi, Salmonella typhi, Valsa sp., Micrococcusluteusand Staphylococcus aureus). The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were also determined from the methanolic extracts.The results suggested that the plantscould be exploited and utilised in the management of various infectious diseases and their tissue extracts might have important roles in pharmaceuticals and preservatives. Key words: Antimicrobial activity, solvent, extraction, mangrove, Bhitarkanika, Sanctuary, MIC, MBC, MFC. I. INTRODUCTION India is a varietal emporium of medicinal plants. Currently majority of people are depending up on traditional medicines for their primary healthcare. Numerous studies have shown that medicinal plants are rich sources of bioactive constituents among which mangroves are one of them which display medicinalproperty and have a major role against pathogens along with commercial importance. Thus, it is very much necessary to characterize diverse types of medicinal plants for their antimicrobial potential.Mangroves aregenerally woody plant, which are found between the sea and land areas.They are inundated to survive in salty soils that would kill most other kinds of plants.The Bhitarkanikasanctuaryregion of the eastern Indian state of Odisha have many different species of mangrove plants. The stressful extreme habitat involving daily changes in pH of soil and water,