www.wjpps.com Vol 3, Issue 9, 2014. 1478 Ferdous et al. World Journal of Pharmacy and Pharmaceutical Sciences EVALUATION OF ANTIMICROBIAL SCREENING OF BARKS & LEAVES EXTRACT OF ALBIZIA LEBBECK Md. Reyad-Ul-Ferdous 1,2* , Md. Zahirul Islam Khan 2 , Nawfel Abdullah 3 , Afroja Nuri Chandni 3 , Umme Habiba Keka 3 , Zasharatul Islam 4 , Tazmel Haque 2 . 1 Department of Pharmacy, Progati Medical Institute, Dhaka-1207, Bangladesh. 2 Department of Pharmacy, State University of Bangladesh, Dhaka 1205, Bangladesh. 3 Department of Pharmacy, East West University, Dhaka-1219, Bangladesh. 4 Department of Pharmacy, University of Asia Pacific, Dhaka-1209, Bangladesh. ABSTRCT Albizzia lebbeck belonging to the Leguminosae family has been investigated for antimicrobial activities. The powdered stem bark & leaf was extracted with methanol. The concentrated extract was then partitioned with pet-ether, carbon Tetrachloride and chloroform. The pet-ether, carbon tetrachloride and chloroform soluble fractions of the crude methanolic extract of this plant were subjected to microbiological investigation by the disc diffusion method. The results compared with a standard Antibiotic, kanamycin. The pet-ether and chloroform soluble fractions showed moderate to strong antimicrobial activity having the zone of inhibition range from 8.66±0.4mm to 10.66±1.24mm and 8.5±0.81mm to 10.66 ±1.2mm respectively, whereas mild to moderate inhibitory activity was found by carbon tetrachloride fractions and methanol soluble fraction having the zone of inhibition range from 8.33±0.47mm to 10±0.51mm and 8.66±0.1.2mm to 9.66±0.94mm respectively. Aqueous soluble fraction showed no antimicrobial activity against the tested microorganism. Key words: Albizzia lebbeck; antimicrobial activity. INTRODUCTION Herbal medicine suggested to the use of any plant’s seeds, roots, berries, leaves, flowers or bark for medicinal purposes [1] . Since 3000 years herbal medicine used to treat several Article Received on 13 July 2014, Revised on 08 August 2014, Accepted on 28 August 2014 *Correspondence for Author Md. Reyad-Ul-Ferdous Department of Pharmacy Progati Medical Institute Dhaka-1207, Bangladesh. WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES SJIF Impact Factor 2.786 Volume 3, Issue 9, 1478-1485. Research Article ISSN 2278 – 4357