Vol.:(0123456789) 1 3 Adsorption (2018) 24:637–645 https://doi.org/10.1007/s10450-018-9969-7 Regularities of adsorption of water-soluble vitamins on the surface of microdispersed sintered detonation nanodiamond S. N. Lanin 1,4  · S. A. Platonova 2  · A. E. Vinogradov 1  · К. S. Lanina 1  · P. N. Nesterenko 1,3 Received: 6 April 2018 / Revised: 29 June 2018 / Accepted: 16 August 2018 / Published online: 28 August 2018 © Springer Science+Business Media, LLC, part of Springer Nature 2018 Abstract Adsorption of water-soluble vitamins, including ribofavin (В 2 ), nicotinamide (PP, B 3 ), pyridoxine (B 6 ), cyanocobalamine (В 12 ) from water-organic solutions on microdispersed sintered detonation nanodiamond (MSDN), modifed in diferent ways, was studied using high-performance liquid chromatography (HPLC). The efect of composition (from 5% to 80 v/v % of CH 3 CN) and рН (рН 2.7/6.0) of mobile phase, as well as temperature of chromatographic column (t c  = 45/65 °C) on vitamins adsorption was studied. Nonlinear dependences of the sorbate retention factors on the acetonitrile content in the mobile phase are found out, indicating the variation of specifc and non-specifc interactions of vitamins with MSDN surface. Based on the obtained results, the conditions for chromatographic separation of the mixture of water-soluble vitamins in isocratic mode of HPLC on MSDN are optimized. Keywords Adsorption · Microdispersed sintered detonation nanodiamond · Acid–base properties · Water-soluble vitamins · High-performance liquid chromatography · Hydrophilic chromatography Electronic supplementary material The online version of this article (https://doi.org/10.1007/s10450-018-9969-7) contains supplementary material, which is available to authorized users. * S. N. Lanin silica2012@gmail.com 1 Chemistry Department, Physical Chemistry Division, Lomonosov Moscow State University, 1–3 Leninskie Gory, Moscow, Russian Federation 119991 2 Samara National Research University, 34 Moskovskoye shosse, Samara, Russian Federation 443086 3 Australian Centre for Research on Separation Science, University of Tasmania, Hobart, TAS 7001, Australia 4 Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Moscow, Russian Federation 119071