International Journal of Advanced Biotechnology and Research (IJBR) ISSN 0976-2612, Online ISSN 2278–599X, Vol-9, Issue-2, 2018, pp637-641 http://www.bipublication.com Research Article A cross sectional study on adverse perinatal outcome in cases with poor biophysical profile Iqra Jamil, Hafiz Mubashir Farooqui and Muhammad Bilal 1 Woman Medical Officer, THQ Hospital Ahmedpur East 2 Medical Officer, THQ Hospital Ahmedpur East 3 Medical Officer, BHU Dera Nawab Sahib ABSTRACT Objective: Tostudy of adverse perinatal outcome in patients with poor biophysical profile. Materials and Methods: This cross sectional study was conducted at Department of Obstetrics &Gynecology THQ Hospital, Ahmedpur East from January 2017 to June 2017. Total 100 patients between 20-35 years, with poor biophysical profile (A score of < 8 out of 10 by taking 5-parameters) screened on ultrasonographic examination, with singleton pregnancy confirmed by ultrasound and with 32-42 weeks of gestation calculated by last period of menstruation and confirmed by ultrasound were included.Adverse perinatal outcome i.e. cesarean section and poor APGAR score was assessed. Results: Total 100 patients were selected for this study. Mean age was 26 ± 43 years and mean gestational age of the patients was 37.78 ± 2.66 weeks. Total 45 (45%) patients belonged to age group 20-25 years followed by 32 (32%) patients belonged to age group 26-30 years and 23 (23%) patients belonged to age group 31-35 years. Cesarean section was performed in 75 (75%) cases and total 92 (92%) patients found with Poor APGAR Score Conclusion: Frequency of adverse perinatal outcome such as cesarean section and Apgar score at 5 minutes in patients with poor biophysical profile was high. Keywords: Poor biophysical profile, cesarean section, Apgar score, gestational age. INTRODUCTION Perinatal period is the most vulnerable period in the life of an individual and the rate of death during this period is higher than any other period of life. Pre term births, infection, hypertensive disease and intrapartum asphyxia are cited as most important contributors for perinatal mortality. 1 Almost 2/3rd of perinatal deaths occur due to obstetrical factors, perinatal hypoxia and infection, which are preventable causes. To address this problem various antenatal foetal surveillance methods have been devised in the past few decades and the search for best is still ongoing. Antepartum foetal testing is a compilation of methods devised to differentiate normal from compromised foetuses prior to onset of labour. The main techniques for foetal assessment are non-stress test (NST), contraction stress test (CST), biophysical profile, foetal movement count and modified biophysical profile and umbilical artery Doppler velocimetry. 2 The NST and CST were two primary methods available for foetalsurveillance but are poor predictors of an asphyxiated infant. Biophysical profile is the combination of NST and dynamic real-time B mode ultra-sonographic assessment of certain foetal parameters. It is a clinical tool that integrates level of dynamic biophysical activities into a usable standard. 3 It