International Journal of Science and Healthcare Research Vol.7; Issue: 1; Jan.-Mar. 2022 Website: ijshr.com Research Paper ISSN: 2455-7587 International Journal of Science and Healthcare Research (www.ijshr.com) 215 Vol.7; Issue: 1; January-March 2022 Effect of Open Kinetic Chain on Functional Activities of Patients with Knee Osteoarthritis Waode Riska Astuti Aini 1 , Ikhsan Nasution 1 , Roni Gunawan 2 , Isidorus Jehaman 3 1 Sekolah Tinggi Ilmu Kesehatan Siti Hajar, Medan 2 Leturer at Public Health Faculty, Institut Kesehatan Helvetia, Medan 3 Institut Kesehatan Medistra, Lubuk Pakam Corresponding Author: Roni Gunawan DOI: https://doi.org/10.52403/ijshr.20220134 ABSTRACT In doing daily activities, limbs of the lower extremities are the most important parts of the body. The knee is the main joint to support the body that the joint cartilage becomes inflamed which can cause pain so it can interfere to its functional activities. Nowadays, our society cannot be separated from all physical activities that involve personal or group activities. Walking, squatting, going up and down stairs, and even running are the most physical activities done by the society. Osteoarthritis is a process of degeneration and repairmen of connective tissue, cartilage, synovium, and subchondral bone. Interventions can be given in the form of exercises improving the ability of functional activities, namely open kinetic chain which this exercise can accelerate blood circulation, prevent contractures, increase muscle strength or muscle strength, relax muscles and knee joints. The aim of this study was to determine the effect of open kinetic chain exercise and increased functional activity on knee osteoarthritis. This study used a quasi- experimental and one group pre and post-test design. The sample of this study was 12 people who had been characterized by the inclusion and exclusion criteria. Measurement of the functional activity value was carried out by women and the results of the study were analyzed using the repeated ANOVA measurable test. The data analysis test showed that the open kinetic chain can increase functional activity on knee osteoarthritis from time to time with an increasing average value of 12% in patients’ functional activity within 3 treatments and 24% within 6 treatments. Keywords: Open Kinetic Chain; Functional Activity; Osteoarthritis Knee INTRODUCTION Performing daily activities, the most important part of the body is the limbs of the lower extremities. The knee is the main joint that supports the body so that the knee is prone to inflammation or inflammation which can cause pain so that its functional activities can be disrupted. Until now, society cannot be separated from all physical activities that involve personal and group activities. Physical activity that is often done by the community is walking, squatting, going up and down stairs and even running. Meanwhile, WHO as quoted by Suhendriyo (2014) stated that around the world, osteoarthritis affects approximately 151 million people, and in Southeast Asia there are 24 million people with osteoarthritis. The prevalence of knee and hip osteoarthritis is higher than other joints because these two joints support the body's weight more. It is said that the prevalence of hip osteoarthritis is 7.4% in women, (8%) higher than men (6.7%). While the knee prevalence is 12.2% for women (14.9%) higher than for men (8.7%) followed by an increase in age (Ismaningsih, 2018). Meanwhile, the National Centers for Health Statistics estimates that there are 15.8 million (12%) adults between the ages of 25-74 years who have complaints of