20 International Journal of Pharmacology and Clinical Sciences, Vol 10, Issue 1, Jan-Mar, 2021 Research Article Int J Pharmacol. Clin. Sci Yousef Ahmed Alomi * , BSc. Pharm, MSc. Clin Pharm, BCPS, BCNSP, DiBA, CDE Critical care clinical pharmacists, TPN clinical pharmacist, Freelancer Business Planner, Content Editor and Data Analyst, Riyadh, SAUDI ARABIA. Nouf Hassan Alamoudi, PharmD Umm Al-Qura University, Makkah, SAUDI ARABIA. Sabah Alanazi, B.D.S Prince Sultan Medical Military City, Riyadh, SAUDI ARABIA. Abeer Hussin Almasoudi, BSc.Pharm Director, Administration of research and studies, Ministry of Health, Tabuk, SAUDI ARABIA. Correspondence: Dr. Yousef Ahmed Alomi, BSc. Pharm, MSc. Clin Pharm, BCPS, BCNSP, DiBA, CDE Critical care clinical pharmacists, TPN Clinical Pharmacist, Freelancer Business Planner, Content Editor and Data Analyst, P.O.BOX 100, Riyadh-11392, Riyadh, SAUDI ARABIA. Phone no: +966504417712 E-mail: yalomi@gmail.com ABSTRACT Objectives: Spontaneous reporting systems are indispensable as they aid perceive serious unknown adverse drug reaction (ADR). To assess the physician’s perceptions and attitudes of adverse drug reaction reporting in the Kingdom of Saudi Arabia. Methods: It was a cross-sectional study with an authenticated survey distributed to different physicians and dentists in Saudi Arabia. A self-administered electronic survey involved of demographic data and perception of the ADR reporting system and factor facilitated or prevented reporting system. Results: The total number of participants was 151. Of those, 111 (73.5%) were physicians, while dentists were 39 (26.5%). The average score physician’s perception about the prominence of the ADR reporting system was 4.46, with a statistically noteworthy difference within answers of each component (p<0.05). The average score of the physician’s perception of factors that enabled the ADR reporting system was 4.13 with a statistically momentous difference within answers of each component (p<0.05). The average scores of perception physicians were 3.13, with a statistically signifcant difference between the responses of each facet (p<0.05). Conclusion: The physicians’ perception of ADR and related issues was optimistic. The physicians request periodic training of ADR identifcation and reporting program. The pharmacist plays a perilous responsibility to improve the ADR system with healthcare providers. Key words: Physician, attitude, Perception, Reporting, Adverse drug reaction, Saudi Arabia Received: 15-09-2021; Accepted: 10-11-2021 Copyright: © the author(s), publisher and licensee International Journal of Pharmacology and Clinical Sciences. Tis is an open-access article distributed under the terms of the Creative Commons Attri- bution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Tis is an open access article distributed under the terms of the Creative Commons Attribution-Non- Commercial-ShareAlike 4.0 License Access this article online WWW.ijpcs.net DOI: 10.5530/ijpcs.2021.10.4 Attitude and Perception of Physicians towards Adverse Drug Reaction Reporting in Saudi Arabia INTRODUCTION In 1969, the WHO well-defned Adverse Drug Reactions (ADRs) as any noxious unintended reaction to a drug which happen at normal doses employed in the prophylaxis, diagnosis or the treatment of diseases. When healthcare professionals distinguish ADR reports through preceding information about it, they have inadequate training about the ADR reporting process, so that undesirable efect on perception or might barriers avert reporting; then lead to an underreporting delinquent. Also, imperfect knowledge leads to it. Over the past twenty years, more than forty studies have deliberated ADR reporting or pharmacovigilance and physicians’ perceptions. Te physicians’ perception of ADR and reporting system was showed with promising results in more than 24 studies and systemic review with 32 studies. More than 80% or 90% of physicians felt it vital to report ADR and should be instructed for all physicians to report the ADR. However, various reason depresses reporting; for instance, did not know how to report 26-60% or dearth time 29-50%. [1-24] Many studies were conducted to assess perception or attitude toward ADR reporting or pharmacovigilance between healthcare professionals in Saudi Arabia. At King Saud medical city, Riyadh 399 participants (52 physicians of participants), the results specify to 93.8% of all participants decided that ADR reporting should be made required for healthcare professionals and 94.5% settled that it improves patient safety. [9] In Al-Khobar at King Fahd Hospital of the University, 331 participants (161 physicians of participant), the outcomes were designated to 87.1% agreed that ADRs need to be described and 75.9% decided that it is obligatory. [6] In Jeddah city, 337 hospital physicians participant; the results showed that 90% of them had a positive attitude toward ADRs, ADRs reporting and monitoring system. [5] In a multi-center study in Saudi Arabia, 336 participants designated 86% agreed that ADR reporting is a professional obligatory, while 26% of participants didn’t know how to submit an ADR report. [10] Most preceding international or local studies did not comprise factors afecting physicians’ perceptions like gender or age, qualifcations, positions, or years of experiences showed in Saudi Arabia. Also, the validation and dependability of the survey was not used in many of the studies. As a result, the current study will deliberate the perception only with factors afecting perception using validation and reliability methods. Te current study’s objective is to state the physician’s perception of the ADR reporting system in Saudi Arabia and factoring afection. METHODS It examines a self-administered electronic survey and cross-sectional design of physicians’ perception of reporting ADRs in Saudi Arabia. All physicians or dentists who functioned at