Copyright © Society of Animal Science, Department of Livestock & Avian Science, Wayamba University of Sri Lanka http://www.wayambajournal.com Wayamba Journal of Animal Science – ISSN: 2012-578X; P1460 - P1466, 2016 First Submitted October 20, 2016; Number 1474474654 FIELD STUDY ON EFFICACY OF RED PEPPER (Capsicum Annum) ALONG WITH ANTIBIOTICS AGAINST NEWCASTLE DISEASE IN BROILER AT NARAIL SADAR UPAZILLA, BANGLADESH S. M. Hanif 1 , Mirza Mienur Meher 1 , Gopal Chandra Biswas 2 and AKM Mostafa Anower 1* 1 Department of Microbiology and Public Health, Faculty of Animal Science and Veterinary Medicine, Patuakhali Science and Technology University, Patuakhali, Bangladesh; 2 Bangladesh Veterinary Council, 48 Kazi Alauddin Road, Dhaka, Bangladesh Corresponding author: - anower@pstu.ac.bd This study was carried out to determine the efficacy of red pepper in controlling Newcastle Disease (ND) along with some symptomatic antibiotic and supportive therapy. A total of 1110 broiler from two farms were used in this study. The results revealed that the inclusion of red pepper (8 pieces per liter water) along with combined antibiotics produce higher efficacy in controlling ND, where survival rate was 92.35% in one farm (Farm A) and 90.5% in another farm (Farm B) containing 600 broilers at the age of 19 days. Overall mortality reduces to 15.88% and 18.5% of Farm A and Farm B, respectively. After treatment with red pepper the average body weight was recorded 1.57 kg and 1.6 kg at the age of 35 days in two farms respectively. Therefore, the study revealed that inclusion of red pepper helps to control the ND in broiler. When red pepper act as natural drug and widely used for prophylactic treatment then small scale farmers will be capable to produce with cost effectively. It is therefore recommended that further research is essential to know the antiviral activity of red pepper in poultry. Keywords: Red Pepper, Antibiotics, Newcastle Disease, Broiler Newcastle Disease (ND) is considered to be one of the most important viral diseases in chickens throughout the world and has a devastating effect on poultry production in most countries (Alexander, 2003). ND or Ranikhet Disease constitutes the most serious epizootic poultry disease throughout the world, particularly in low-income food- deficit countries (Aini, 1990 and Guèye, 2002). The majority of farmers keep their chickens in a scavenging system, where the main source of feed is household refuse and picking from the surroundings. The infection still occurs in Bangladesh every year in the form of epidemic and appears to cause up to 40-60% of the total mortality in poultry population creating one of the major problems in the development of poultry industry in Bangladesh (Chowdhury et al., 1982). ND is caused by the Newcastle disease virus (NDV) which is also called avian paramyxovirus serotype 1 (APMV-1) is a single stranded, enveloped, negative sense RNA virus belonging to the genus Rubulavirus of subfamily Paramyxovirinae and family Paramyxoviridiae (Barbezange et al., 2005 and Mayo, 2002). The transmission of NDV occurs through newly introduced birds, selling or giving away sick birds, exposure to fecal and other excretions from infected birds and contact with contaminated feed, water, equipment and clothing (Tu et al., 1998). Hot red pepper is one of the most important herbs, which is widely used in human feed all over the world, its originated from central and South America and its belonged to Solanaceae family, genus Capsicum is belong to the most heavily and frequently consumed as spices throughout the world (Kobata et al., 1998). Capsicum annum is the first introduced worldwide which is divided into two categories: sweet (or mild) pepper and hot (or chilli) pepper. Capsicum annum is the most spread in term of P 1460 Copyright © Society of Animal Science, Department of Livestock & Avian Science, Wayamba University of Sri Lanka http://www.wayambajournal.com