– Spalte 1 – Determination of Ampicillin in Human Plasma by Solid-phase Extraction- Liquid Chromatography-Tandem Mass Spectrometry (SPE-LC-MS/MS) and its Use in Bioequivalence Studies Talita Mota Gonçalves 1 , Danilo César Galindo Bedor 1 , Luís Renato Pires de Abreu 1 , Carlos Eduardo Miranda de Sousa 1 , Clarice M. Bueno Rolim 2 , Davi Pereira de Santana 1 1 NUDFAC–Núcleo de Desenvolvimento Farmacêutico e Cosmético – NUDFAC-UFPE, Centro de Biodisponibilidade / Bioequivalência, Departamento de Ciências Farmacêuticas, Universidade Federal de Pernambuco, Recife, Pernambucojok? (Brazil) 2 CEBIFAR–Centro de Estudos de Bioequivalência e Farmacocinética, Departamento de Farmácia Industrial, Universidade Federal de Santa Maria, j city? (Brazil) Corresponding author: Prof. Davi Pereira de Santana, PhD, Rua Professor Arthur de Sá s/n, Cidade Universitária, CEP 50740-520, Recife, Pernambuco (Brazil); e-mail: d-santana@bol.com.br Author: Some sentences were insufficient in terms of grammar or understanding. Please check the changed sen- tences marked by a square black symbol (j). Thank you. Eiliger Abzug der Korrektur Urgent proof Rücksendung eines genehmigten Abzuges erbeten an: Please return one corrected copy to: ECV · Editio Cantor Verlag · Baendelstockweg 20 88326 Aulendorf (Germany) Fax + 49 (0)7525 940 127 · Tel. + 49 (0)7525 9400 e-mail: redaktion.af@ecv.de AF AF 0207-01 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 Key words j Ampicillin, bioequivalence study, human plasma, solid- phase extraction-liquid chro- matography-tandem mass spectrometry j Antibacterials j CAS 69-53-4 Arzneimittel-Forschung (Drug Research) 2007;57(j): j–j