www.ijcrt.org © 2020 IJCRT | Volume 8, Issue 4 April 2020 | ISSN: 2320-2882 IJCRT2004565 International Journal of Creative Research Thoughts (IJCRT) www.ijcrt.org 3951 A REVIEW ON TOPICAL GEL Prem Samundre*, Surendra Dangi, Teena Patidar, Shubham Maroti Shende. School of pharmacy and research, People’s University, Bhanpur, Bhopal (MP) India, 462031 ABSTRACT Topical gels or formulations have many advantages as compared to other conventional dosage form. Topical gels are less toxic and more effective than other dosage form. Topical gels are best choice for treat local infections and skin problems because of it directly apply on the skin or in the site. Topical gels provide action direct to the site of action. Topical gels exclude the GI irritation and metabolism of drug by which the bioavailability of drug is greater. Drug-Drug interaction and Food drug interaction is also not possible in the case of topical gels. Gels have better penetrating power because gel consists two phase. In this review a detailed study about gel, its preparation, characteristics and evaluation parameter was done. Keywords :- Topical gel, ideal characteristics of gel, and evaluation parameter. INTRODUCTION Topical gels are semi solid homogenous preparation used to cure and treat topical diseases. Gels are more hydrophilic in nature so the rate of released drug or active ingredient was fast. A gel consist of two component, three dimensional cross linked material which contain proportionally large amount of liquid medium to form adequate rigid network which immobilized the liquid continuous phase.³´⁴ Inorganic particles and organic macromolecules both are used to form a structural network of gel. In chemical gel the particles are associated with permanent covalent bonding while physical topical gels are associated by weaker and reversible secondary intermolecular forces like hydrogen bonding, electrostatic interactions, hydrophobic interaction and Vander Waals forces.¹´² IDEAL PROPERTIES OF TOPICAL GEL ⁵  The gel should be clear and homogenous.  The gel should be easily broken when shear or force is applied during shaking the container.  The gel should be inert in nature.  The gel should be not sticky.  The gel should be never interacting with other formulation component.  The gel should be stable.  It should not be irate the skin or any part where the gel is applied.