Al- Mustansiriyah J. Sci. Vol. 23, No 6, 2012 117 Study of Some Mirabilis jalapa L. Leaves Components and Effect of Their Extracts on Growth of Pathogenic bacteria Mustafa Taha Mohammed Department Of Chemistry, College Of Science, Al-Mustansiriyah University, Baghdad, Iraq. Tahabiochem@Yahoo.Com, Received 14/3/2012 – Accepted 20/6/2012 صة الخ لة عباس ق نباتدة في أورالة الموجو اّ ئية الفعلكيميات المكونااسة معرفة ات الدر شملMirabilis jalapa , لمركباتوعة من اجم يحتويان على مالكحوليلمائي و امستخلصينولي الدراسة أن محل إذ أظهرت ال ينات والبروتقلويداتت والتنجالية والراالفينوة والعفصية وديكوسيي الك بينمالصابونياتحتوي على ا ت فونويدات . والف صر المعدلعنايق ل الدقيلتحل اثبت ال على تراكيز منءها احتوالنباتوراق ا نيةK وNa وFe وهي161.2 ,19 18.7 μg/ml يات منالي , وكمى التو علZn وCa وهي12, 14.2μg/ml وكميات علىCd , Cu وPb وهي0.8 ,0.3,0.1 μg/ml . وى التوالي علئها علىعدم احتوا , وCr . لتركيزلبكتريا أذ لوحظ أن لواع مختلفة من اية على أنالكحوللمائية وت امستخلصاس تأثير ال كما در0.5 ط نمو بكتريا تجاه تثبي اّ /مل تأثيرا فعلغم مProteus mirabilis وE.coli وStaphylocoous aureus ص الكحولي .مستخله ال خاصة تجا ABSTRACT The chemical components of the Mirabilis jalapa L. leaves in the watery and alcoholic extracts were identified .The results showed that the extract contain : glycosides ,tannins ,phenolic compounds , resins ,alkaloids and proteins ,while the saponins and flavonoids were not found. The results also showed that there were concentrations of the following trace elements in the leaves K , Na , Fe with 161.2 ,19 ,18.7 μg/ml , respectively and concentrations of Zn ,Ca with 14.2 , 12 μg/ml respectively , concentrations Cd ,Cu, Pb with 0.8 ,0.3,0.1 μg/ml respectively ,and Cr were not founds. The effects of these extracts on growth of different bacteria were studied, has been found that 0.5 mg/ml concentration was effective inhibitor of growth of Staphylocoous aureus , E.coli and Proteus mirabilis . INTRODUCTION Mirabilis jalapa Linn (Nyctaginaceae), known as four o'clock, maravilla, belle de nuit, buenas tardes, Dondiego de noche, jalap, noche buena,[1,2] Mirabilis jalapa L. is widely used to treat dysentery, diarrhea, muscular pain, and abdominal colics in different countries [3- 5] and its extract has antibacterial, antiviral, and antifungal functions [6- 8]. In China, Mirabilis jalapa L. is widely distributed and commonly used with its root, and has been used as traditional Chinese medicine and ethnic drug to treat diabetes [9,10], constipation [11], genitourinary system disorders and injuries [12].Several constituents of the Mirabilis jalapa plant have been isolated from the root and aerial part, including some rotenoids (mirabijalones A-D, boeravinones C and F), an isoquinoline derivate [13], as well as terpenoids, steroids, phenolic compounds, stigmasterol, p-sitosterol, p-sitosterol- p-D-glucoside, ursolic acid, mirabalisoic acid, mirabalisol, trigonellin and an antiviral