_____________________________________________________________________________________________________ *Corresponding author: E-mail: olanike771@gmail.com; Microbiology Research Journal International 23(1): 1-6, 2018; Article no.MRJI.34852 ISSN: 2456-7043 (Past name: British Microbiology Research Journal, Past ISSN: 2231-0886, NLM ID: 101608140) Microbial Synthesis of Polyhydric Alcohol by Saccharomyces cerevisiae Simiat Olanike Jimoh 1* , Lawal Aminat Olajumoke 1 , Ashorobi Abdul Adisa 1 , Oyekanmi Ezekiel Abiodun 1 , Bakare Rashidat Ikeoluwa 1 , Adefioye Nafisat Adesola 1 and Ibrahim Ramon Adegboyega 1 1 Microbiology Unit, Department of Biological Sciences, College of Natural and Applied Sciences, Fountain University, Osogbo, Osun State, Nigeria. Authors’ contributions This work was carried out in collaboration between all authors. Author SOJ designed the study, performed the statistical analysis, wrote the protocol and wrote the first draft of the manuscript. Authors LAO, AAA and OEA managed the analyses of the study. Authors BRI, ANA and IRA managed the literature searches. All authors read and approved the final manuscript. Article Information DOI: 10.9734/MRJI/2018/34852 Editor(s): (1) Eliton da Silva Vasconcelos, Department of Physiological Sciences, Federal University of São Carlos – UFSCar, Rod. Washington Luiz, São Carlos, SP, Brazil. Reviewers: (1) Selma Gomes Ferreira Leite, Federal University of Rio de Janeiro, Brazil. (2) Eliton da Silva Vasconcelos, Federal University of São Carlos, Brazil. (3) Jose Ismael Acosta Rodriguez, Universidad Autónoma de San Luis Potosí, México. Complete Peer review History: http://www.sciencedomain.org/review-history/23557 Received 15 th June 2017 Accepted 4 th January 2018 Published 8 th March 2018 ABSTRACT Aim: Synthesis of polyhydric alcohol from agricultural residue using Saccharomyces cerevisiae. Study of Design: Submerged fermentation process, biomass yield and reducing sugar analysis, non-reducing sugar analysis, extraction and quantification of sugar monomers and polyhydric alcohols. Place and Duration of Study: Microbiology Unit, Department of Biological Sciences, College of Natural and Applied Sciences, Fountain University Osogbo, Osun State, Nigeria between October 2015 and July 2016. Methodology: Synthetic route for the production of polyhydric alcohol through sugar reduction under submerged fermentation using Saccharomyces cerevisiae MP2 isolated from fermented beverages was investigated. Biomass yield, reducing sugar concentration (DNS method) and non- reducing sugar (Anthrone method) were analysed. The crude extract obtained after fermentation Original Research Article