Copyright@ Nataniele Piol | Biomed J Sci & Tech Res | BJSTR. MS.ID.006265. 31113 Case Report ISSN: 2574 -1241 A Peculiar Type of Haemangioma that Poses Some Problems in Pathological Differential Diagnosis with Angiosarcoma Nataniele Piol 1 *, Gabriele Gaggero 1 , Carlo Terrone 2 , Guglielmo Mantica 2 and Bruno Spina 1 1 Department of Anatomic Pathology, Ospedale Policlinico San Martino, Genoa, Italy 2 Department of Urology, Ospedale Policlinico San Martino, Genoa, Italy *Corresponding author: Nataniele Piol, Department of Anatomic Pathology, Ospedale Policlinico San Martino, Genoa, Italy DOI: 10.26717/BJSTR.2021.39.006265 ARTICLE INFO ABSTRACT Received: September 26, 2021 Published: October 04, 2021 Citation: Nataniele Piol, Gabriele Gag- gero, Carlo Terrone, Guglielmo Mantica, Bruno Spina. A Peculiar Type of Hae- mangioma that Poses Some Problems in Pathological Differential Diagnosis with Angiosarcoma. Biomed J Sci & Tech Res 39(2)-2021. BJSTR. MS.ID.006265. Vascular tumors are predominantely superficial lesions spanning from benign through intermediate grade to malignant neoplasm with various histological appearance and subtypes. Deep seated vascular lesions, especially in retroperitoneum, are usually angiosarcomas. Anastomising hemangioma is a rare benign neoplasm originally described in urogenital organs with histological features mimicking angiosarcoma. It was subsequently found in other sites, retroperitoneum being one of the least common. In particular we herein report a case of anastomosing hemangioma in perirenal adipose tissue. Keywords: Kidney; Peri-Renal; Anastomosing Hemangioma; Hemangioma; Angiosarcoma Introduction Anastomising hemangioma is a rare benign neoplasm originally described in urogenital organs [1]. Even if it is seldom encountered in routine diagnostic sign out, it is important for pathologist to know about its existence because it has quite alarming histological features that could lead to an erroneous diagnosis of angiosarcoma. After its original description, this neoplasm was subsequently found in other sites, retroperitoneum being one of the least common [2], especially without any concomitant renal lesion. We herein report a rare case of retroperitoneal anastomosing hemangioma. Case Report A 49-years old male patient came to our attention in January 2019 for the incidental finding of a 16x12 mm right peri-renal lesion at the superior abdominal images of a chest computed tomography (CT) scan. The patient had a positive medical history for pulmonary tuberculosis and asthma. He did not complain of hematuria, flank pain or any other symptom. An abdominal contrast CT scan was performed, which confirmed the presence of the abovementioned lesion (Figure 1). A 5x7,8 cm hepatic hemangioma completed the scenario. The patient also underwent a positron emission tomography with fluorodeoxyglucose (18F-FDG-PET) scan which did not find an increased glucose metabolism. At the presentation the patient had haemoglobin 16,2 g/dl, creatinine 1,3mg/dl. The patient underwent a laparoscopic exeresis of right peri-renal lesion with preservation of the kidney and adrenal gland. No postoperative complications were observed. Peri- renal fat tissue including the above-mentioned lesion was sent to Anatomic Pathology Laboratory and fixed overnight in 10% formalin. Gross examination of perirenal fat tissue revealed a