TRAUMA HEMOSTASIS AND OXYGENATION RESEARCH POSITION PAPER ON REMOTE DAMAGE CONTROL RESUSCITATION: DEFINITIONS, CURRENT PRACTICE, AND KNOWLEDGE GAPS Donald H. Jenkins,* Joseph F. Rappold, † John F. Badloe, ‡ Olle Berse ´ us, § COL Lorne Blackbourne, || Karim H. Brohi, ¶ Frank K. Butler,** LTC Andrew P. Cap, †† Mitchell Jay Cohen, ‡‡ Ross Davenport, §§ Marc DePasquale, |||| Heidi Doughty, ¶¶ Elon Glassberg,*** ††† Tor Hervig, ‡‡‡ Timothy J. Hooper, §§§ Rosemary Kozar, |||||| Marc Maegele, ¶¶¶ Ernest E. Moore,**** Alan Murdock, †††† Paul M. Ness, ‡‡‡‡ Shibani Pati, §§§§ Col Todd Rasmussen, |||||||| Anne Sailliol, ¶¶¶¶ Martin A. Schreiber,***** Geir Arne Sunde, ††††† Leo M. G. van de Watering, ‡‡‡‡‡ Kevin R. Ward, §§§§§ Richard B. Weiskopf, |||||||||| Nathan J. White, ¶¶¶¶¶ Geir Strandenes,****** †††††† and Philip C. Spinella** |||||||| ‡‡‡‡‡‡ *Department of Surgery, Mayo Clinic, Rochester, Minnesota; † Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania; ‡ Transfusion Medicine, Blood Banking (American Society of Clinical Pathology), Netherlands Military Blood Bank; § Department of Transfusion Medicine, O ¨ rebro University Hospital, O ¨ rebro, Sweden; || Commander, US Army Institute of Surgical Research, San Antonio, Texas; ¶ Trauma Sciences, Barts and the London School of Medicine, and Trauma & Vascular Surgery at the Royal London Hospital, London, UK; **Committee on Tactical Combat Casualty Care, Joint Trauma System, Joint Base San Antonio, Texas; †† Coagulation and Blood Research, US Army Institute of Surgical Research, JBSA Fort Sam Houston, Texas; ‡‡ Department of Surgery University of California-San Francisco, San Francisco, California; §§ Centre for Trauma Sciences, Blizard Institute, Bart’s & the London School of Medicine, Queen Mary University of London, London, UK; |||| Deployment Medicine International, Gig Harbor, Washington; ¶¶ Transfusion Medicine NHS Blood and Transplant, Birmingham, UK; ***The Trauma & Combat Medicine Branch, Surgeon General’s HQ, Israel Defense Forces, Ramat Gan; and ††† Department of Military Medicine, Hebrew University, Jerusalem, Israel; ‡‡‡ Blood Bank, Haukeland University Hospital, and Department of Clinical Science, University of Bergen, Norway; §§§ UK Defence Medical Services, Anaesthetic Department, Frenchay Hospital, Bristol UK; |||||| Department of Surgery, Memorial Hermann Hospital, University of Texas Medical School at Houston, Houston, Texas; ¶¶¶ Department for Traumatology, Orthopedic Surgery and Sportsmedicine CologneYMerheim Medical Center, Cologne, Germany; ****Vice Chairman for Research, Department of Surgery, University of Colorado Denver, Colorado; †††† Surgeon General for Trauma, Air Force Medical Operations Agency, Lackland AFB, Texas; and Division of Trauma and General Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; ‡‡‡‡ Transfusion Medicine Division, Johns Hopkins Medical Institutions, Baltimore, Maryland; §§§§ Blood Systems Research Institute and University of California, San Francisco, California; |||||||| US Army Institute of Surgical Research, Joint Base San Antonio, Fort Sam Houston, Texas; ¶¶¶¶ French Military Blood Transfusion Center, Clamart, France; *****Oregon Health & Science University, Portland, Oregon; ††††† Norwegian Air Ambulance Foundation, Drøbak, Norway; ‡‡‡‡‡ Sanquin Blood Supply, Center for Clinical Transfusion Research, Leiden, the Netherlands; §§§§§ Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, Michigan; |||||||||| Department of Anesthesia, University of California, San Francisco, California; ¶¶¶¶¶ Division of Emergency Medicine, Department of Medicine, University of Washington, Seattle, Washington; ******Norwegian Naval Special Operation Commando and †††††† Department of Immunology and Transfusion Medicine, Haukeland University Hospital, Bergen, Norway; and ‡‡‡‡‡‡ Division of Pediatric Critical Care, Department of Pediatrics, Washington University in St Louis, St Louis, Missouri Received 29 Oct 2013; first review completed 18 Nov 2013; accepted in final form 8 Jan 2014 SHOCK, Vol. 41, Supplement 1, pp. 3Y12, 2014 Address reprint requests to Donald H. Jenkins, MD, Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. E-mail: jenkins.donald@mayo.edu. Disclosures of interest: P.C.S.: TerumoBCT, Entegrion, Octapharma, grant recipient for NIH/NHLBI, US Department of Defense. E.E.M.: Grant recipient for US Department of Defense. R.D.: Grant recipient for TEM Innovations, Haemonetics. H.D.: UK Defence Medical Services. M.M.: Consultant for Biotest, CSL Behring, LFB, TEM International. P.M.N.: Consultant for TerumoBCT. J.F.R.: US Department of Defense. R.B.W.: NHLBI/NIH, FDA, US DOD, CaridianBCT, CSL-Behring. N.J.W.: National Institutes of Health NCCR-NCATS KL2 TR000421, Washington Life Sciences Discovery Fund, University of Washington Coulter Translational Research Award, and University of Washington Institute for Translational Health Sciences and is and is cofounder, board member, and consultant to Stasys Medical Corp and reports no conflicts of interest related to this work. Travel support for this work was provided by NIH NCCR-NCATS KL2 TR000421. The opinions or assertions contained herein are the private views of the authors and are not to be construed as official, or as reflecting the views of the UK Defence Medical Services, US Army, US Department of Defense, Norwegian Armed Forces Medical Services, the French Armed Forces, Armed Forces of the Netherlands, Israel Defense Forces, or the Swedish Armed Forces. DOI: 10.1097/SHK.0000000000000140 Copyright Ó 2014 by the Shock Society Copyright © 2014 by the Shock Society. Unauthorized reproduction of this article is prohibited.