Open Access Case Report Journal of Dermatology Research Chen HH | Volume 1; Issue 3 (2020) | JDR-1(3)-013 | Case Report Citation: Chen HH. An Unusual Skin Manifestation by Mycoplasma Pneumoniae without Pulmonary Infection. J Dermatol Res. 2020;1(3):1-5. DOI: http://dx.doi.org/10.46889/JDR.2020.1303 An Unusual Skin Manifestation by Mycoplasma Pneumoniae without Pulmonary Infection Hsuan-Hsiang Chen 1* 1 Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan *Corresponding Author: Hsuan-Hsiang Chen, MD, Department of Dermatology, National Taiwan University Hospital, 7, Chung-Shan South Road, Taipei, Taiwan; E-mail: beauty101@gmail.com Received Date: 15-10-2020; Accepted Date: 05-11-2020; Published Date: 13-11-2020 Copyright © 2020 by Chen HH. All rights reserved. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Pulmonary infections are often caused by Mycoplasma pneumoniae. However, extra pulmonary manifestations are also reported. Mycoplasma pneumonia associated severe mucositis with relative few skin rash has recently been described as a new clinical disease named Mycoplasma Pneumoniae-Induced Rash and Mucositis (MIRM). A 14-year-old girl who developed exuberant mucositis, as well as multiple tense bullae and several targetoid lesions were found on the face, trunk and 4 limbs, but no obvious pulmonary manifestation was found. The laboratory examinations showed elevated M. pneumoniae IgM antibodies. Due to this unique clinical presentation, MIRM was considered and differentiated from Toxic Epidermal Necrolysis (TEN), Stevens-Johnson Syndrome (SJS), or Erythema Multiforme (EM). MIRM may be reconsidered as a specific cutaneous manifestation with or without pulmonary infection. Keywords Mycoplasma Pneumoniae; Mucositis; Erythema Multiforme