769 International Journal of Progressive Sciences and Technologies (IJPSAT) ISSN: 2509-0119. © 2021 International Journals of Sciences and High Technologies http://ijpsat.ijsht-journals.org Vol. 25 No. 2 March 2021, pp. 494-506 Corresponding Author: Maged MN 494 3D Bioprinting for Tissue Engineering Application Review Maged MN 1 , Mohamed MN 2 , Lamia H. Shehata 3 , And Laila Abdelfattah 4 1 Mazahmiya Hospital, Ministry of Health, Kingdom of Saudi Arabia, Department of ob/gyn, 2 King Fahd Hospital, Ministry of Health, Kingdom of Saudi Arabia, Department of Surgery, 3 Care National hospital, Department of Radiology, 4 University of Leeds, Faculty of Engineering (Mechatronics), UK. Abstract – Three-dimensional (3D) printing (rapid prototyping or additive fabricating innovations) has gotten significant consideration in different fields in the course of recent many years. Tissue engineering uses of 3D bioprinting, specifically, have attracted the attention of numerous researchers. 3D platforms delivered by the 3D bioprinting of biomaterials (bio-inks) empower the recovery and rebuilding of different tissues and organs. These 3D bioprinting methods are helpful for creating platforms for biomedical and regenerative medication and tissue engineering applications, allowing quick production with high-accuracy and control over size, porosity, and shape. In this review, we present an assortment of tissue designing applications to make bones, vascular, skin, ligament, and neural structures utilizing an assortment of 3D bioprinting strategies. Keywords – Bioprinting, Scaffold, Bio-ink, Tissue engineering. I. INTRODUCTION Recently, regenerative medication and tissue engineering research has been coordinated toward the recovery, substitution, or reclamation of injured functional living tissues and organs, like bone, vascular, skin, neural, and ligament [1,2,3, 4, 5]. These tissue engineering applications require the experiences of researchers from various fields, just as particular information on biomaterials, cell science, biocompatibility, imaging, and the characterization of platform surfaces [6, 7]. Perhaps the main parts of tissue engineering are the manufacture of permeable three-dimensional (3D) frameworks that give the suitable climate to recovering tissues and organs. 3D platforms for use in tissue engineering field are created utilizing a different assembling techniques and biomaterials [8,9]. A several significant qualities should be considered in these applications [10]: First and in particular, a tissue engineering framework should be biocompatible. Second, created 3D frameworks ought to be biodegradable or bioabsorbable so that tissue at last replaces the platform. Third, the ideal platform ought to have mechanical properties reliable with the tissue to be embedded. Fourth lastly, the 3D platform ought to be promptly manufacturable in an assortment of shapes and sizes. A several strategies have been produced for manufacturing 3D platforms utilizing engineered and characteristic polymers, including gas foaming, phase separation, electrospinning, and melt molding [11, 4, 12, 13]. These framework manufacture strategies can't exactly control the pore size, shape of the platform, or the inward channel design inside the platform. In addition, there are limits on the ability to create platforms utilizing cells.