_____________________________________________________________________________________________________ # Resident, † Professor, *Corresponding author: E-mail: divitshah@hotmail.com; Journal of Pharmaceutical Research International 33(64A): 170-176, 2021; Article no.JPRI.80786 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Study of Platelet Indices in Patients with Metabolic Syndromes: A Study Protocol Divit P. Shah a#* , Sunil Kumar b† , Sourya Acharya a† and Shilpa Bawankule b† a Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Deemed to be University, Wardha, India. b Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences Deemed to be University, Wardha, India. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2021/v33i64A35316 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/80786 Received 20 October 2021 Accepted 25 December 2021 Published 30 December 2021 ABSTRACT Background: Metabolic syndrome is a syndrome of unified metabolic disorder which includes abdominal obesity (AO), hypertension, hypertriglyceridemia (HTG), hyperglycemia and decreased high-density lipoprotein (HDL). Metabolic syndrome subjects are exposed to greater chances to have insulin resistance, visceral fat accumulation, atherogenic changes to the vessels, abnormal lipid levels and abnormal functioning of endothelium. Platelets play a key role in hemostasis. The mean platelet volume (MPV) and platelet’s proportion are indicators of platelet function. This study aims to find the correlation between various platelet indices in patients with Metabolic syndromes. Methods: This prospective study is planned to be conducted in AVBRH, Wardha. Patients anthropometric parameters like height, weight, blood pressure, waist circumference, hip circumference and biochemical parameters such as fasting blood glucose, serum triglycerides, serum HDL, and mean platelet volumes will be assessed. Total 130 subjects will be assessed and data will be analyzed to estimate a correlation between platelet indices and metabolic syndromes. Expected Results: A significant correlation is expected between various platelet indices in patients of different metabolic syndromes. Study Protocol