This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/uog.22178 Anatomical and timely assessment of protein expression of angiotensin- converting enzyme 2, SARS-CoV-2 specific receptor, in fetal and placental tissues: new insight for perinatal counseling V. Faure-Bardon 1,2 , P. Isnard 3,4 , N. Roux 3 , M. Leruez-Ville 1,5 , T. Molina 3 , B. Bessieres 3 , Y. Ville 1,2 * 1. EA 73-28, Université de Paris, Paris, France. 2. AP-HP, Department of Obstetrics and Fetal Medicine, Hospital Necker-Enfants Malades., Paris, France 3. AP-HP, Department of Histology, Embryology and Cytogenetics, Hospital Necker- E.M., Paris, France 4. Institut National de la Santé et de la Recherche Médicale (INSERM), U1151, CNRS UMR 8253, Hospital Necker-E.M, Department of Growth and Signaling, Université de Paris, Paris, France 5. AP-HP, Virology Laboratory, Hospital Necker-E.M, Paris, France * Corresponding author Pr Yves Ville Hôpital Necker-Enfants Malades, Service de gynécologie-obstétrique, 149 rue de Sèvres, 75015 Paris, France Email : ville.yves@gmail.com Short title : ACE-2 expression in placenta and fetal organs Keywords: ACE-2, protein expression, fetal organs, placenta, sars-CoV-2, vertical transmission This article is protected by copyright. All rights reserved.