_____________________________________________________________________________________________________ # Junior Resident; † Professor; ¥ Professor and Head; *Corresponding author: E-mail: sg2638@gmail.com; Journal of Pharmaceutical Research International 33(51A): 33-37, 2021; Article no.JPRI.76796 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) Povidone Iodine Ointment vs Cadexomer Iodine Ointment in Management of the Chronic Wound: A Study Protocol Shubham Gupta a*# , Raju Kamalrao Shinde a† and Sangita Shinde b¥ a Department of Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (M), Wardha, Maharashtra, India. b Department of Pharmacology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (M), Wardha, Maharashtra, India. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2021/v33i51A33464 Editor(s): (1) Dr. Aurora Martínez Romero, Juarez University, Mexico. (2) Dr. Debarshi Kar Mahapatra, Rashtrasant Tukadoji Maharaj Nagpur University, India. (3) Dr. Farzaneh Mohamadpour, University of Sistan and Baluchestan, Iran. Reviewers: (1) Fulya Ustun-Alkan, Istanbul University, Turkey. (2) Sapna Raghav, NBGSM College, India. Complete Peer review History: https://www.sdiarticle4.com/review-history/76796 Received 07 September 2021 Accepted 15 November 2021 Published 20 November 2021 ABSTRACT Introduction: Chronic wound and its care has always been a health burden for patient, health care professionals and the entire health care system. There have been certain topical preparations available in market today for application in chronic wound management. In our study, we are comparing effects of cadexomer and povidone iodine ointment in context of reduction in bacterial overload, slough reduction, facilitations of granulation tissue formation, reduction in size of the wound and ultimately in percentage of wound healing and its cost of management. Aim: Comparison of outcome of Povidone Iodine Ointment and Cadexomer iodine Ointment in management of the wound. Methodology: This cross section observational study has been conducted among 40 patients Study Protocol