Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/bdi.12828 This article is protected by copyright. All rights reserved. DR. IVES CAVALCANTE PASSOS (Orcid ID : 0000-0001-6407-8219) DR. ELISA BRIETZKE (Orcid ID : 0000-0003-2697-1342) DR. TOMAS HAJEK (Orcid ID : 0000-0003-0281-8458) DR. MARTIN ALDA (Orcid ID : 0000-0001-9544-3944) MR. BARTHOLOMEUS C.M. HAARMAN (Orcid ID : 0000-0002-9006-8863) PROF. ROGER S MCINTYRE (Orcid ID : 0000-0003-4733-2523) DR. LARS KESSING (Orcid ID : 0000-0001-9377-9436) PROF. ANNE DUFFY (Orcid ID : 0000-0002-5895-075X) DR. FLAVIO KAPCZINSKI (Orcid ID : 0000-0001-8738-856X) Article type : Review TITLE PAGE Machine learning and big data analytics in bipolar disorder: A Position paper from the International Society for Bipolar Disorders (ISBD) Big Data Task Force Authors: Ives Cavalcante Passos, MD, PhD 1 ; Pedro Ballester 2 ; Rodrigo Coelho Barros, PhD 2 ; Diego Librenza-Garcia, MD 3 ; Benson Mwangi, PhD 4 ; Boris Birmaher, MD 5 ; Elisa Brietzke, MD, PhD 6 ; Tomas Hajek, MD, PhD 7,10 ; Carlos Lopez Jaramillo, MD, MSc, PhD 8 ; Rodrigo B. Mansur, MD, PhD 9 ; Martin Alda, MD 7 ; Bartholomeus C.M. (‘Benno’) Haarman, MD 11 ; Erkki Isometsa, MD, PhD 12 ; Raymond W Lam, MD 13 ; MD; Roger S. McIntyre, MD, FRCPC 14 ; Luciano Minuzzi, MD, PhD 3 ; Lars Vedel Kessing, MD, DMSc 15 ; Lakshmi N. Yatham, MBBS 13 ; Anne Duffy, MD, MSc 6 ; Flavio Kapczinski MSc, MD, PhD, FRCPC 3 . 1. aorator o Moleular shatr an Bolar sorer roram ostal e Clnas e orto lere rorama e s-rauao em suatra e Cnas do Comportamento, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. 2. School of ehnolo onta nersae Catla o o rane o ul, Rio Grande do Sul, RS, Brazil. 3. Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada. 4. UT Center of Excellence on Mood Disorders, Department of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX, USA.