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Andrew J. Spillane,*† MD, FRACS
Meagan E. Brennan,*† FRACGP, FASBP
*Northern Clinical School, University of Sydney,
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doi: 10.1111/j.1445-2197.2009.05048.x
Understanding chronic testicular pain: a psychiatric perspective
The management of chronic testicular pain is difficult. Patients in
whom a clear organic diagnosis cannot be made may be subjected to
a range of surgical treatments of unclear benefit. Many of the clinical
features of chronic testicular pain ‘syndrome’ overlap with well-
recognized somatoform disorders. Thus, the pain some patients
experience may in fact represent underlying psychological conflict
that is not surgically remedial.
Chronic testicular pain is described as persistent or recurrent
episodic pain localized to the testis for at least 3 months.
1
This
encompasses a myriad of clinical scenarios: from the patient with
unremitting low-grade testicular ache, to episodes of acute scrotal
pain with pain-free intervening periods. The main organic causes of
scrotal pain that must be considered in each case include infection,
testicular torsion and malignancy. Most acute organic causes can be
excluded by a thorough history and physical examination, supple-
mented where indicated by urine and urethral cultures or PCR (Poly-
merase Chain Reaction) and scrotal ultrasonography. However,
finding an organic diagnosis for a patient with chronic pain is more
difficult. Despite modern advances in diagnostic evaluation, these
patients typically undergo more than four procedures each,
3
and no
cause is found in 25%.
1
Invasive treatment options have included transrectal ultrasound-
guided pelvic plexus block, pulsed radiofrequency, epididymec-
tomy, orchidectomy and testicular denervation.
2,4
Evidence for their
use is limited to small case series, and their efficacies vary widely.
Orchidectomy, previously seen as a last resort, has a reported
efficacy of 20–75%.
1,3,5
Testicular denervation has an efficacy of
71–96%,
6,7
and one large series of 79 patients demonstrated durable
relief in 71%.
8
However, almost 30% of patients still underwent an
unnecessary mutilating procedure.
Recent guidelines suggest early involvement of a multidisci-
plinary pain team.
2,9
Its role includes initial pain management and
further evaluation with procedures such as diagnostic nerve blocks.
Medical pain management is first attempted using trials of antibiot-
ics, anti-inflammatories, low-dose antidepressants, anticonvulsants,
membrane-stabilizing agents and opiates
2
. They are complemented
by transcutaneous electrical nerve stimulation, lumbar sympathetic
blocks or repeated phentolamine infusions,
2
and other treatments,
such as rehabilitative physiotherapy for pelvic floor musculature.
9
The psychiatric considerations reported in most articles about
testicular pain have focused on the assessment and treatment of
concomitant depression, rather than on the aetiology of the pain. Yet
in one study of 48 men, 56% met criteria for a somatoform disorder,
and 27% met criteria for major depression.
10
This suggests that the
psychological contribution to such presentations may be more sig-
nificant than previously identified. Somatoform disorders are a con-
troversial collection of psychiatric disorders related to somatization.
Somatization is the tendency to communicate psychological distress
as somatic and medically unexplained symptoms. There are seven
somatoform disorders described in the Diagnostic and Statistical
Manual of Mental Disorders (DSM IV, Table 1).
11
Their common
Table 1 Diagnostic and Statistical Manual of Mental Disorders (DSM IV)
criteria for somatoform disorder
Criteria for pain disorder
(1) Pain in one or more anatomical sites is the predominant focus of
the clinical presentation and is of sufficient severity to warrant
clinical attention
(2) The pain causes clinically significant distress or impairment in
social, occupational or other important areas of functioning
(3) Psychological factors are judged to have an important role in the
onset, severity, exacerbation or maintenance of pain.
(4) The symptom or deficit is not intentionally produced or
feigned (as in factitious disorder or malingering).
(5) The pain is not better accounted for by a mood, anxiety or
psychotic disorder.
Code as follows:
Pain disorder associated with psychological factors.
Pain disorder associated with both psychological factors and a
general medical condition.
DSM IV details the features required for diagnosis of psychiatric disorders. All
criteria for pain disorder must be fulfilled for a positive diagnosis.
676 Perspectives
© 2009 The Authors
Journal compilation © 2009 Royal Australasian College of Surgeons