J Med Assoc Thai Vol. 93 No. 6 2010 643 Correspondence to: Roongpisuthipong A, Department of Obstetrics and Gynecology, Siriraj Hospital, Bangkok 10700, Thailand. Phone: 0-2419-4999, Fax: 0-2418-2662. E-mail: siarp@mahidol.ac.th Current Therapy for Condyloma Acuminata of the Patients Attending Female STD Unit, Siriraj Hospital Anuvat Roongpisuthipong MD*, Amphan Chalermchockcharoenkit MD*, Manopchai Thamkhantho MD*, Isarin Thanaboonyawat MD*, Chanon Neungton MD* * Gynecologic Infectious Diseases and Female Sexually Transmitted Disease Unit, Department of Obstetrics and Gynecology, Siriraj Hospital, Bangkok, Thailand Objective: To describe the treatment pattern of condyloma acuminata in female. Material and Method: The 5-year medical records of 449 women treated for genital condyloma acuminata at the Gynecologic Infectious Diseases and Female Sexually Transmitted Disease (GID-FSTD) unit were reviewed. Data included the distribution of age, client by category, anatomical site and size, serologically coexisting sexually transmitted infection (STI), and treatment modalities. Results: About half, 50.1%, of treatment was the application of topical trichloroacetic acid; followed by podophylline in the proportion of 35.5%. While the electric cauterization and imiquimod applications were uncommon therapy. Two-fifth of the subjects, 40.7%, was completely cured, and the remaining cases required additional management. Conclusion: The present setting, the wide range of treatment available is reflection of the fact that there is no ideal management. Keywords: Condyloma acuminata, Trichloroacetic acid, Podophylline, Electric cauterization, Imiquimod Prevention of genital tract condyloma acuminata had recently drawn public attention since it was well documented of relationship to carcinoma of cervix uteri. One of the most popular preventions of such genital human paillomavirus (HPV) infection is HPV vaccination (1-4) . In spite of a big wave of HPV vaccination, prevention for carcinoma of cervix (1) , treatment of genital HPV infection is an important issue concerning individual transmission in couples or in the epidemiological point of view. The past five years data about genital condyloma acuminata at the Gynecologic Infectious Diseases and Female Sexually Transmitted Disease (GID-FSTD) unit, Siriraj Hospital showed certain number of patients attended the unit and had been treated for HPV (5,6) with some success but some had resistant-to-treatment outcomes (5,7,8) . The patient’s economic burden for rather long follow-up visits according to treatment plan appointments creates an increasing loss to follow-up rate followed by incomplete treatment among those patients. The review of medical records of women treated for genital condyloma acuminata was analyzed to describe the treatment pattern of condyloma acuminata in females. Material and Method The 5-year medical records of women treated for genital condyloma acuminata at GID-FSTD unit, between 1 October 2004 to 30 September 2008, were obtained. Data included the distribution of age, client by category, anatomical site and size, serologically coexisting sexually transmitted infection (STI), and treatment modalities. The associated sexually transmitted infection (STI) (9) such as herpes genitalis and cytological study of cervical cancer were attained. The outcome of the treatment was compared to the standard regimens for improvement of the current modern therapy (10-14) . The laboratory investigation included VDRL, HBsAg, HIV antibody, and concurrent STI was determined as well (15) . The categorical data was described in the number and percent. J Med Assoc Thai 2010; 93 (6): 643-6 Full text. e-Journal: http://www.mat.or.th/journal