Cardiol Cardiovasc Med 2022; 6 (2): 196-205 DOI: 10.26502/fccm.92920255 Cardiology and Cardiovascular Medicine Vol. 6 No. 2 – April 2022. [ISSN 2572-9292] 196 Research Article Eccentricity of Aortic Annulus and Distance of Origin of Left Main and Right Coronary Arteries from Adjacent Aortic Leaflets in Non- Stenotic Aortic Valves by TEE 3D Echocardiography Hakimeh Sadeghian 1* , Arash Jalal Omidi 1 , Arash Jalali 2 , Parto Siavosh 3 1 Dr. Shariati hospital, Tehran university of medical sciences, North Kargar street, Tehran, Iran 2 Department of research, Tehran heart center, Tehran university of medical sciences, Iran 3 School of medicine, Tehran university of medical sciences, Iran *Corresponding author: Hakimeh Sadeghian, Dr. Shariati hospital, Tehran university of medical sciences, North Kargar street, Tehran, Iran Received: 12 April 2022; Accepted: 18 April 2022; Published: 22 April 2022 Citation: Hakimeh Sadeghian, Arash Jalal Omidi, Arash Jalali, Parto Siavosh. Eccentricity of Aortic Annulus and Distance of Origin of Left Main and Right Coronary Arteries from Adjacent Aortic Leaflets in Non-Stenotic Aortic Valves by TEE 3D Echocardiography. Cardiology and Cardiovascular Medicine 6 (2022): 196-205. Abstract To measure the size of the aortic Annulus (AN) and Left Ventricular Outflow Tract (LVOT) in different views and distance between right and left coronary ostia from aortic annulus by Transesophageal (TEE)3D echocardiography in patients with normal aortic valves. Method: 31 patients (51.5% F) underwent TEE3D.Full-volume of aortic valve was saved by TEE3D.AN was measured in 3 planes: two orthogonal lines in short-axis plane (D1 & D2), sagittal (D3) and coronal (D4) planes,diameter of LVOT 5-10 mm below AN was measured in sagittal and coronal views (D5 & D6). Area and perimeter of AN were measured and the annulus according to area and perimeter was calculated. Distance of left main and RCA from aortic leaflets and length of left coronary cusp were measured. All measurements were done in mid-systole. Results: Aortic annulus in sagittal (D3) is smaller than coronal (D4), mean difference=1.97mm, P=0. 002.In 50% of subjects, D4 was greater than D3 more than 1.9 mm. D3 and D4 are not significantly different with D5 and D6. D