Open Journal of Modern Neurosurgery, 2021, 11, 107-113 https://www.scirp.org/journal/ojmn ISSN Online: 2163-0585 ISSN Print: 2163-0569 DOI: 10.4236/ojmn.2021.112013 Apr. 27, 2021 107 Open Journal of Modern Neurosurgery Brain Metastasis of Uterine Leiomyosarcoma: A Case Report and Review of the Literature Fernand Nathan Imoumby 1,2*# , Yao Christian Hugues Dokponou 1,2* , Franck Kouakou 1,2 , Hajar El Agouri 2,3 , Abad Cherif El Asri 1,2 , Miloud Gazzaz 1,2 1 Department of Neurosurgery, Mohammed V Military Teaching Hospital, Rabat, Morocco 2 Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco 3 Department of Anatomy Pathology, Mohammed V Military Teaching Hospital, Rabat, Morocco Abstract The metastases of uterine leiomyosarcoma to the brain are exceptional and such cases are seldomly reported in the literature. The diagnosis is based on CT and brains MRI findings, in association with a gynecological history of cancer. Their management still stays without guidelines, and the surgical total resection is known to be the only way to influence positively the prognosis and save patient lives. We report a rare case of a 46 years old woman who underwent a hysterectomy and bilateral salpingo-oophorectomy 5 years ear- lier and presented with the right hemiparesis and whose CT scan and MRI of the brain showed cerebral lesions related to brain location of uterine lei- omyosarcoma. The patient underwent surgery for gross total tumor resection, followed by adjuvant radiotherapy, and was doing well after surgery. Three months later she was admitted for recurrences and died after two months of palliative care. Keywords Uterine Leiomyosarcoma, Brain Metastasis, Case Report 1. Introduction Brain metastases frequently occur secondary to poorly controlled primary lung, breast, melanoma, colorectal and renal tumors [1]. These tumors are the most common sources of brain metastases in adults. Uterine leiomyosarcoma (ULMS) is a rare entity among malignant gynecologic tumors with a very poor prognosis *Joint first authors. # Corresponding author. How to cite this paper: Imoumby, F.N., Dokponou, Y.C.H., Kouakou, F., El Agouri, H., El Asri, A.C. and Gazzaz, M. (2021) Brain Metastasis of Uterine Leiomyosar- coma: A Case Report and Review of the Literature. Open Journal of Modern Neu- rosurgery, 11, 107-113. https://doi.org/10.4236/ojmn.2021.112013 Received: March 18, 2021 Accepted: April 24, 2021 Published: April 27, 2021 Copyright © 2021 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access