153 © Springer International Publishing AG, part of Springer Nature 2018
P. Angelos, R. H. Grogan (eds.), Diffcult Decisions in Endocrine Surgery,
Diffcult Decisions in Surgery: An Evidence-Based Approach,
https://doi.org/10.1007/978-3-319-92860-9_14
B. James (*)
Section of Endocrine Surgery, Division of Surgical Oncology, Department of Surgery, Beth
Israel Deaconess Medical Center, Boston, MA, USA
e-mail: bjames1@bidmc.harvard.edu
R. H. Grogan
Baylor College of Medicine, Michael E. DeBakey Department of Surgery, Endocrine Surgery,
Baylor St. Luke’s Medical Center, Houston, TX, USA
e-mail: Raymon.Grogan@bcm.edu
E. L. Kaplan
Department of Surgery, The University of Chicago, Chicago, IL, USA
P. Angelos
Department of Surgery and MacLean Center for Clinical Medical Ethics,
The University of Chicago, Chicago, IL, USA
e-mail: pangelos@surgery.bsd.uchicago.edu
14
Prophylactic Versus Selective Central
Neck Dissection in Pediatric Papillary
Thyroid Cancer
Benjamin James, Raymon H. Grogan, Edwin L. Kaplan,
and Peter Angelos
Abstract
The frst case of thyroid carcinoma in a child was described in 1902. Following this,
Crile published the frst case series of pediatric thyroid cancer in 1959, whereby he
characterized pediatric thyroid cancer in 18 children. He noted that pediatric thyroid
cancer was more commonly metastatic to cervical lymph nodes and to the lungs
than was described in the adult population. Despite fnding these cancers to be more
aggressive than in adults, only one of the patients died of thyroid cancer and four of
them were alive with lung metastases. This publication spawned many subsequent
studies confrming these fndings. As a result, there has been much debate on the
appropriate surgical treatment of thyroid cancer in the pediatric population both
with respect to the extent of surgery and the use of radioactive iodine.
Keywords
Pediatric thyroid cancer · Adolescent thyroid cancer · Prophylactic neck
dissection · Papillary thyroid cancer