Accepted Manuscript Synthesis of new heterocyclic compounds based on pyrazolopyridine scaffold and evaluation of their neuroprotective potential in MPP + -induced neurodegeneration Jabrane Jouha, Mohammed Loubidi, Jamila Bouali, Salha Hamri, Abderrafia Hafid, Franck Suzenet, Gérald Guillaumet, Taner Dagcı, Mostafa Khouili, Fadime Aydın, Luciano Saso, Güliz Armagan PII: S0223-5234(17)30084-3 DOI: 10.1016/j.ejmech.2017.02.019 Reference: EJMECH 9215 To appear in: European Journal of Medicinal Chemistry Received Date: 18 October 2016 Revised Date: 5 February 2017 Accepted Date: 7 February 2017 Please cite this article as: J. Jouha, M. Loubidi, J. Bouali, S. Hamri, A. Hafid, F. Suzenet, G. Guillaumet, T. Dagcı, M. Khouili, F. Aydın, L. Saso, G. Armagan, Synthesis of new heterocyclic compounds based on pyrazolopyridine scaffold and evaluation of their neuroprotective potential in MPP + -induced neurodegeneration, European Journal of Medicinal Chemistry (2017), doi: 10.1016/ j.ejmech.2017.02.019. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.