Accepted Manuscript Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents Simone Brogi, Margherita Brindisi, Bhupendra P. Joshi, Salvatore Sanna Coccone, Silvia Parapini, Nicoletta Basilico, Ettore Novellino, Giuseppe Campiani, Sandra Gemma, Stefania Butini PII: S0960-894X(15)30042-1 DOI: http://dx.doi.org/10.1016/j.bmcl.2015.09.007 Reference: BMCL 23088 To appear in: Bioorganic & Medicinal Chemistry Letters Received Date: 30 July 2015 Revised Date: 2 September 2015 Accepted Date: 4 September 2015 Please cite this article as: Brogi, S., Brindisi, M., Joshi, B.P., Coccone, S.S., Parapini, S., Basilico, N., Novellino, E., Campiani, G., Gemma, S., Butini, S., Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents, Bioorganic & Medicinal Chemistry Letters (2015), doi: http://dx.doi.org/ 10.1016/j.bmcl.2015.09.007 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.