대한수혈학회：18권 3호, 2007 － 177 －  접수일：2007 9 5, 승인일：2007 11 28 책임저자： 현  120-752 시 대문구 신촌동 134 연대학교 과대학 단검학교실 TEL: 02) 2228-2444, FAX: 02) 313-0956, E-mail: hyunok1019@yuhs.ac.kr 1단위 적혈구 수혈의 적정성 평가 박용정ㆍ박윤희ㆍ이양순ㆍ백은정ㆍ김신영ㆍ김현옥 연대학교 과대학 단검학교실 = Abstract = Evaluating the Appropriateness of a Single Unit Transfusion Yongjung Park, Younhee Park, Yangsoon Lee, Eun Jung Baek, Sinyoung Kim, Hyun Ok Kim Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea Background: The domestic quantity of blood components consumed has been decreasing since 2002, but the rate of a single unit RBC transfusion (SUT) has been on the increase. In the past, a SUT was regarded as an uncesssary procedure, but currently is considered as an effective method to maintain a minimal hemoglobin concentration for physiological needs. We investigated the actual conditions of a SUT. Methods: We analyzed 800 cases of SUTs performed at a tertiary care university hospital between March 2006 March and February 2007. The subjects of the study were divided into a surgical group (n=561) and medical group (n=239) for the purpose of RBC unit usage and were analyzed by groups and ordering departments, with an analysis of the pre and post-transfusion hemoglobin concentration and hematocrit values. The distribution according to the pre and post-transfusion hemoglobin ranges were calculated. Results: The mean hemoglobin concentration increment of the surgical group was significantly lower than that of the medical group (P＜0.0001) and the mean pre and post-transfusion hemoglobin concentrations of the medical group were lower than that of the surgical group (P＜0.0001). Approximately 26% cases of the SUTs performed in the surgical group were appropriate, based on a post-transfusion hemoglobin concentration below 10 g/dL. In the medical group, about 75% of the SUTs were appropriate based on a pre-transfusion hemoglobin concentration below 9 g/dL. Conclusion: Most transfusions are decided based on various clinical situations and opinions of the clinicians. Therefore, continuous evaluation of the appropriateness of transfusion is necessary. In our study, the appro- priateness of a SUT was estimated indirectly based on the pre and post-transfusion hemoglobin concentration. Consequently, policies and strategies for performing asingle unit RBC transfusion are required. (Korean J Blood Transfus 2007;18:177-187)  Key words: Single unit, Transfusion, Hemoglobin concentration