Accepted Manuscript Synthesis and biological evaluation of thiazole derivatives as novel USP7 in- hibitors Chao Chen, Jiemei Song, Jinzheng Wang, Chang Xu, Caiping Chen, Wei Gu, Hongbin Sun, Xiaoan Wen PII: S0960-894X(17)30030-6 DOI: http://dx.doi.org/10.1016/j.bmcl.2017.01.018 Reference: BMCL 24594 To appear in: Bioorganic & Medicinal Chemistry Letters Received Date: 9 September 2016 Revised Date: 2 January 2017 Accepted Date: 9 January 2017 Please cite this article as: Chen, C., Song, J., Wang, J., Xu, C., Chen, C., Gu, W., Sun, H., Wen, X., Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors, Bioorganic & Medicinal Chemistry Letters (2017), doi: http://dx.doi.org/10.1016/j.bmcl.2017.01.018 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.