_____________________________________________________________________________________________________ *Corresponding author: Email: sohailafatima@gmail.com; Journal of Cancer and Tumor International 6(4): 1-5, 2017; Article no.JCTI.38725 ISSN: 2454-7360 Ganglioneuroma Involving Deep Facial Structures - A Case Report Bouvier Francis Valere D’sa 1 , Sohaila Fatima 2* and Nazima Haider 2 1 Department of Laboratory Medicine, Aseer Central Hospital, Abha, Kingdom of Saudi Arabia. 2 Department of Pathology, King Khalid University, Abha, Kingdom of Saudi Arabia. Authors’ contributions This work was carried out in collaboration between all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/JCTI/2017/38725 Editor(s): (1) Sung-Chul Lim, Industry-Academic Cooperation Foundation, Chosun University, South Korea. Reviewers: (1) Lauritano Dorina, University of Milan-Bicocca, Italy. (2) Yasushi Shibata, University of Tsukuba, Japan. (3) Ana Pires Gonçalves, Universidade do Algarve, Portugal. Complete Peer review History: http://www.sciencedomain.org/review-history/22900 Received 9 th November 2017 Accepted 19 th January 2018 Published 27 th January 2018 ABSTRACT Ganglioneuroma is a rare peripheral neuroblastic tumor originating from the neural crest. It is a benign tumor involving posterior mediastinum and retroperitoneum. We present a case of 12-year- old boy who was diagnosed with ganglioneuroma involving deep facial structures - infratemporal fossa extending to adjacent structures. Keywords: Ganglioneuroma; deep face; infratemporal fossa. 1. INTRODUCTION Ganglioneuroma (GN) is an uncommon benign entity of the peripheral neuroblastic tumors (PNTs) that occurs commonly in childhood [1]. It arises from cells in the sympathetic ganglia and adrenal medulla. It is a fully differentiated tumor containing mature tissues. It is rare compared with other benign neural tumors such as schwannoma and neurofibroma but outnumbers neuroblastomas (NB) along the sympathetic axis by about 3 to 1. It is most often located in the posterior mediastinum, retroperitoneum and uncommonly in adrenal proper [2]. We present a 12-year-old boy who presented with the prominence of left cheek and proptosis of left eye Case Study