Journal of Cancer Therapy, 2021, 12, 136-145 https://www.scirp.org/journal/jct ISSN Online: 2151-1942 ISSN Print: 2151-1934 DOI: 10.4236/jct.2021.123015 Mar. 25, 2021 136 Journal of Cancer Therapy Gastric Adenocarcinoma at the Joliot Curie Institute in Dakar: Epidemiological, Diagnostic and Therapeutic Aspects about 54 Cases Kanta Ka 1* , Doudou Diouf 2,3 , Sidy Ka 2,3 , El Hadj Amadou Sall 1 , Daniele Presti 4 , Mamadou Moustapha Dieng 2,3 , Papa Macoumba Gaye 1,3 , Ahmadou Dem 2,3 1 Radiotherapy Department, CHNU Dalal Jamm, Guédiawaye, Senegal 2 Oncology Department, Institute Joliot Curie, Dakar, Senegal 3 Cheikh Anta Diop University of Dakar, Dakar, Senegal 4 Medical Oncology Service, ICS Maugeri IRCCS SpA, University of Pavia, Pavia, Italy Abstract Objectives: To study the epidemiological, diagnostic, therapeutic and prog- nostic aspects of gastric adenocarcinoma at the Joliot Curie Institute in Da- kar. Materials and Methods: We conducted a retrospective study over a seven-year period from January 2010 to December 2017 at the Joliot Curie Institute in Dakar. All cases of gastric adenocarcinoma proven by fibroscopy followed by histology or proven on the histological analysis of a surgical spe- cimen were taken into account. The parameters studied were age, risk factors, stages of the disease, treatment and prognosis. Results: There were 54 cases of gastric adenocarcinoma over a period of 7 years. The average age was 54.74 years with extremes of 25 and 84 years. A male predominance was noted (35/54). The main risk factors found were alcohol (5/54), tobacco (13/54), Helicobacter pilori (4/54), gastric ulcer (12/54). Epigastralgia was the most frequent clinical manifestation. FOGD was carried out in 77.8% of patients. Histology was obtained before surgery in 40 patients (74.1% of cases) and on the operating room in 14 patients (25.9%). Patients were classified as stage II in 2/54 cases, stage III in 5/54 cases and stage IV in 47/54 cases. Ga- stro-entero-anastomosis was the main surgical procedure performed. Exter- nal radiotherapy was performed in 1/54 patients. Chemotherapy was done in 52/54 patients, 96.3% of the cases. It was palliative in 66.7% of cases, neoad- juvant in 1.9% of cases, adjuvant in 24.1% of cases, perioperative in 3.7% of cases. Mortality was 79.6%. Patient survival times were relatively short: in less than 6 months 24/54 cases, 13/54 cases between 6 - 12 months, 5/54 cases between 13 - 24 months and 6/54 cases beyond 24 months. 6/54 patients were How to cite this paper: Ka, K., Diouf, D., Ka, S., Sall, ElH.A., Presti, D., Dieng, M.M., Gaye, P.M. and Dem, A. (2021) Gastric Adenocarcinoma at the Joliot Curie Insti- tute in Dakar: Epidemiological, Diagnostic and Therapeutic Aspects about 54 Cases. Journal of Cancer Therapy, 12, 136-145. https://doi.org/10.4236/jct.2021.123015 Received: February 18, 2021 Accepted: March 22, 2021 Published: March 25, 2021 Copyright © 2021 by author(s) and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution-NonCommercial International License (CC BY-NC 4.0). http://creativecommons.org/licenses/by-nc/4.0/ Open Access