JPET #193284 1 Title page: Pharmacological Characterization of Abediterol, a Novel Inhaled β2 Adrenoceptor Agonist with Long Duration of Action and a Favorable Safety Profile in Preclinical Models Mònica Aparici, Mireia Gómez-Angelats, Dolors Vilella, Raquel Otal, Carla Carcasona, Marisa Viñals, Israel Ramos, Amadeu Gavaldà, Jorge De Alba, Jordi Gras, Julio Cortijo, Esteban Morcillo, Carlos Puig, Hamish Ryder, Jorge Beleta and Montserrat Miralpeix Primary laboratory of origin: Almirall, R&D Center, Sant Feliu de Llobregat, Barcelona, Spain Almirall, R&D Center, Sant Feliu de Llobregat, Barcelona, Spain (M.A., M.G.-A., D.V., R.O., C.C., M.V., I.R., A.G., J.D.A., J.G., J.C., E.M., C.P., H.R., J.B., M.M.); Department of Pharmacology, Faculty of Medicine, University of Valencia, Valencia, Spain and Ciber Respiratory Diseases (CIBERES), Valencia, Spain (J.C., E.M.); Research Foundation, University General Hospital, Valencia, Spain (J.C.); Clinical Pharmacology Unit, Research Foundation, University Clinic Hospital, Valencia, Spain (E.M.). JPET Fast Forward. Published on May 15, 2012 as DOI:10.1124/jpet.112.193284 Copyright 2012 by the American Society for Pharmacology and Experimental Therapeutics. JPET Fast Forward. Published on May 15, 2012 as DOI:10.1124/jpet.112.193284 Copyright 2012 by the American Society for Pharmacology and Experimental Therapeutics. This article has not been copyedited and formatted. The final version may differ from this version. JPET Fast Forward. Published on May 15, 2012 as DOI: 10.1124/jpet.112.193284 at ASPET Journals on December 15, 2021 jpet.aspetjournals.org Downloaded from