Research Article
Addressing Inpatient Glycaemic Control with
an Inpatient Glucometry Alert System
J. N. Seheult,
1
A. Pazderska,
2
P. Gaffney,
1
J. Fogarty,
1
M. Sherlock,
2
J. Gibney,
2
and G. Boran
1
1
Clinical Chemistry Department, Adelaide and Meath Hospital, Tallaght, Dublin 24, Ireland
2
Department of Medicine, Endocrinology Division, Adelaide and Meath Hospital, Tallaght, Dublin 24, Ireland
Correspondence should be addressed to J. N. Seheult; seheultj@tcd.ie
Received 6 November 2014; Revised 27 May 2015; Accepted 8 June 2015
Academic Editor: Andre P. Kengne
Copyright © 2015 J. N. Seheult et al. Tis is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background. Poor inpatient glycaemic control has a prevalence exceeding 30% and results in increased length of stay and higher rates
of hospital complications and inpatient mortality. Te aim of this study was to improve inpatient glycaemic control by developing
an alert system to process point-of-care blood glucose (POC-BG) results. Methods. Microsof Excel Macros were developed for the
processing of daily glucometry data downloaded from the Cobas IT database. Alerts were generated according to ward location
for any value less than 4 mmol/L (hypoglycaemia) or greater than 15 mmol/L (moderate-severe hyperglycaemia). Te Diabetes
Team provided a weekday consult service for patients fagged on the daily reports. Tis system was implemented for a 60-day
period. Results. Tere was a statistically signifcant 20% reduction in the percentage of hyperglycaemic patient-day weighted values
>15mmol/L compared to the preimplementation period without a signifcant change in the percentage of hypoglycaemic values.
Te time-to-next-reading afer a dysglycaemic POC-BG result was reduced by 14% and the time-to-normalization of a dysglycaemic
result was reduced from 10.2 hours to 8.4 hours. Conclusion. Te alert system reduced the percentage of hyperglycaemic patient-day
weighted glucose values and the time-to-normalization of blood glucose.
1. Introduction
Hyperglycaemia and hypoglycaemia are prevalent in the
inpatient setting. A recent analysis of hospital glucometry
data by Bersoux and Cook from January to December
2012 was conducted on 51.4 million measurements from 2.6
million inpatients. Te authors found that the prevalence of
hypoglycaemia (<4 mmol/L or 70 mg/dL) was 6.1% in non-
ICU patients and 5.6% in ICU patients, while the prevalence
of hyperglycaemia (>10 mmol/L or 180 mg/dL) was substan-
tially higher at 32% in non-ICU patients and 28% in ICU
patients. Te mean point-of-care blood glucose (POC-BG)
was 167 mg/dL for non-ICU patients and 170 mg/dL for ICU
patients. Te authors concluded that increased hospital par-
ticipation in data collection was needed for the development
of optimal practices to manage inpatient dysglycaemia [1].
Numerous studies have shown that improvement in gly-
cemic control results in lower rates of hospital complications
in general medicine and surgery patients [2–6]. In one
study, newly discovered hyperglycaemia was associated with
a higher in-hospital mortality rate (16%) compared with those
patients with a prior history of diabetes (3%) and subjects
with normoglycaemia (1.7%; both < 0.01)[2].
At the opposite end of the glycaemic scale, studies have
shown that in-hospital secondary hypoglycaemia increases
inpatient mortality, likelihood of readmission, and length of
stay [7–9].
Certain clinical situations increase the risk of dysgly-
caemia during a hospital admission. Tese include changes
in caloric or carbohydrate intake especially “nil by mouth”
status or total parenteral nutrition [10]; use of diabetogenic
medications like corticosteroids [11]; failure of medical staf to
make adjustments to glycemic therapy based on daily blood
glucose (BG) patterns [12]; prolonged use of sliding scale
insulin regimens [13]; lack of coordination between insulin
therapy, blood glucose monitoring, and meals [14]; issues
Hindawi Publishing Corporation
International Journal of Endocrinology
Volume 2015, Article ID 807310, 8 pages
http://dx.doi.org/10.1155/2015/807310