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The Relationship between life-time Prevalence
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Objectives : The present study was carried out to determine
the incidence of Bipolar Spectrum Disorders (BSD)
among pregnant women in rural areas of the province of
Isfahan using Mood Disorder Questionnaire (MDQ), and
its relationship with the development of post-partum
depression (PPD). Method : This cohort prospective study
was carried out on all pregnant women in their third
trimester, residing in rural areas covered by Isfahan University
of Medical Sciences. In the first stage, all subjects were
assessed for present depression and life-time BSD, by
Beck Depression Inventory (BDI) and MDQ respectively.
In the second stage, 6-8 weeks after delivery, all women
who did not have depression at the first stage were
screened for postnatal depression using the Edinburgh
Postnatal Depression Scale (EPDS). Results : Results
showed the incidence of 24.65% for PPD. Significant
correlation between life-time prevalence of BSD and
incidence of PPD was shown (p<0.05, r=0.24). The
sensitivity and specificity of the MDQ for predicting PPD
were 46.6% and 75.6% respectively. Its positive and
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Iranian Journal of Psychiatry and Clinical Psychology, Vol. 15, No. 2, Summer 2009, 183-192
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34
Original
Article