J. Neuroscience and Neurological Surgery Copy rights@ Sofia Sabouri et.al. Auctores Publishing LLC – Volume 10(1)-217 www.auctoresonline.org ISSN: 2578-8868 Page 1 of 6 The vertebral Artery Anomalous, Stenosis vs Hypoplasia as the leading cause of Stroke. An anatomical cross-Sectional Study of VA anomalies in Neck three-Dimensional computed Tomography Angiography Farzaneh Mohammadi ¹*, Hussein Soleimantabar ², Fatemeh Mohamadi ³, Sofia Sabouri ⁴ ¹ Box hill Hospital, Eastern Health, Victoria, and Australia. ²Department of Radiology, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ³Department of Radiology, Emam Jafar Sadegh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. ⁴Department of Radiology, Shahid Beheshti University of Medical Sciences/Tehran/ Iran. *Corresponding Author: Farzaneh Mohammadi, Box hill Hospital, Eastern Health, Victoria, and Australia. Received date: October 30, 2021; Accepted date: December 07, 2021; Published date: December 13, 2021 Citation: Farzaneh Mohammadi, Hussein Soleimantabar, Fatemeh Mohamadi, Sofia Sabouri (2021). The vertebral Artery Anomalous, Stenosis vs Hypoplasia as the leading cause of Stroke. An anatomical cross-Sectional Study of VA anomalies in Neck three-Dimensional computed Tomography Angiography. J. Neuroscience and Neurological Surgery. 10(1); DOI:10.31579/2578-8868/217 Copyrights: © 2021 Farzaneh Mohammadi, This is an open-access article distributed under the terms of The Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited Abstract Introduction: A thorough understanding of the vertebral artery (VA) variations and course of the artery and its related branches could significantly enhance the efficacy and safety of interventions involving the neck and spine. Here, we aimed to investigate the incidence of various VA variations in individuals presenting with signs and symptoms of stroke with our neurology team. Material and Method: In this retrospective study we investigate CTA images of patients with signs and symptom of stroke who referred to specialized medical imaging centre. An experienced board-certified radiologist evaluated the CTA images, recording the characteristics of VA, regarding dominance and any possible anomalies. These included anomalous origin, anomalous route, anomalous branching, stenosis, hypoplasia, atresia, thrombosis, and dissection. All data were analyzed using SPSS version 24 and Pearson Chi-Square and Fishers test used for anomaly and gender correlation. Results: A total of 125 patients (53.6% females; mean age, 60.7 (11-87)) were included. In the case of VA dominance, 66.4% of cases were co-dominant while 16.0% were right, and 12.8% were left dominant. Overall, males had more VA anomalies than females, 24.8% and 17.6%, respectively (in general, 42.4% of all participants) (p = 0.020). Among patients, 4.0% (n = 5) had an anomalous origin and anomalous branching was reported in 5 patients (4.0%). Among the variations, significant stenosis (18.4%) and hypoplasia (17.6%) were the most prevalent anomalies with the earliest one having the higher rate. While anomalous branching was reported in 5 patients (4.0%). Conclusions: VA variations are relatively common and should be addressed during procedures involving the neck region and would allow surgeons to avoid life threatening injury. Keywords: vertebral artery; anomalies; ct angiography; significant stenosis; hypoplasia 1. Introduction: The vertebral artery (VA) arises from the respective subclavian artery and connects the opposite site branch to form the basilar artery [1]. The VA is anatomically divided into four segments: V1, preforaminal; V2, foraminal; V3, atlantic; and V4 intracranial [2]. Anatomical variations mainly involve the distal segments of VA (V3 and V4). Several embryological explanations for these variations have been proposed in the literature [3]. With the growing use of vascular angiography, uncommon cases of hypoplasia, origin stenosis, and altered origin have thoroughly been Open Access Research Article Journal of Neuroscience and Neurological Surgery Farzaneh Mohammadi * AUCTORES Globalize your Research