www.proteomics-journal.com Page 1 Proteomics Received: 12 29, 2017; Revised: 05 17, 2018; Accepted: 07 05, 2018 This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/pmic.201700479 . This article is protected by copyright. All rights reserved. Quantitative Proteomic Analysis of Biological Processes and Responses of the Bacterium Desulfovibrio desulfuricans ND132 upon Deletion of its Mercury Methylation Genes Chen Qian, 1,2,¶ Hongmei Chen, 3,¶ Alexander Johs, 3 Xia Lu, 3 Jing An, 3 Eric M. Pierce, 3 Jerry M. Parks, 4 Dwayne A. Elias, 4 Robert L. Hettich, 1,2 Baohua Gu 3* 1 Chemical Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA 2 Graduate School of Genome Science and Technology, University of Tennessee, Knoxville, Tennessee 37996, USA 3 Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA 4 Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, USA ¶ These authors contributed equally. *Corresponding author: Email: gub1@ornl.gov; Phone: (865)-574-7286; Fax: (865)-576-8543 Disclaimer (not for publication) This manuscript has been authored by UT-Battelle, LLC under Contract No. DE- AC05-00OR22725 with the US Department of Energy (DOE). The United States Government retains and the publisher, by accepting the article for publication, acknowledges that the United States Government retains a non-exclusive, paid-up, irrevocable, world-wide license to publish or reproduce the published form of this manuscript, or allow others to do so, for United States Government purposes. The Department of Energy will provide public access to these results of federally sponsored research in accordance with the DOE Public Access Plan (http://energy.gov/downloads/doe-public-access-plan).