www.scholarsresearchlibrary.com t Available online a Scholars Research Library Archives of Applied Science Research, 2016, 8 (8):14-20 (http://scholarsresearchlibrary.com/archive.html) ISSN 0975-508X CODEN (USA) AASRC9 14 Scholars Research Library Adiabatic compressibility, apparent molal volume, apparent molal compressibility and solvation number of substituted 2-oxo-2-H-chromene-3- carbohydrazide derivatives in 70% DMF-Water P. P. Choudhari 1 , D. S. Hedaoo 2 and M. P. Wadekar 1* 1 Applied Chemistry Division, Govt. Vidarbha Institute of Science and Humanities, Amravati, (MS), India 2 Arts, Science and Commerce College, Chikhaldara _____________________________________________________________________________________________ ABSTRACT Ultrasonic study of substituted 2-oxo-2-H-chromene-3-carbohydrazide derivatives in 70% DMF-water at 305K is done. The experimental data is used to calculate adiabatic compressibility, apparent molal volume, apparent molal compressibility and solvation number. These acoustic parameters are used to explain the interaction taking place in the solutions. Keywords: Substituted 2-oxo-2-H-chromene-3-carbohydrazide derivatives, acoustic parameters and interactions in solutions. _____________________________________________________________________________________________ INTRODUCTION Ultrasonic study has wide range of application in material science, agriculture, medicine, biology, industry, oceanography, sonochemistry research due to its non-destructive nature[1-2]. The ultrasonic velocity measurement is used to provide qualitative information about the physical nature and strength of molecular interaction in the liquid mixture[3]. Ultrasonic technique is applied to impart positive effects in food processing such as improvement in mass transfer, food preservation, assistance of thermal treatments and manipulation of texture and food analysis[4].Ultrasonic technique is utilized for measuring the thickness of skin and biological tissues[5]. The determination of ultrasonic properties of pure solvents and their solutions finds wide range of applications in chemical, pharmaceutical, polymer and bio-chemical industries[6]. Ultrasonic technique is used to determine antimicrobial activity of schiff bases[7]. Anti-inflammatory property of phenylalanine analogus as schiff bases is reported[8].Ultrasonic velocity finds extensive application in solution theory and molecular dynamics[9].Ultrasound velocity along with related thermo acoustic parameters have extensively used in the recent years to study molecular interaction in binary and ternary liquid mixtures by number of researchers[10-12]. Acoustic characteristics have studied for sodium salt of N-chloro-p-toluene sulphonamide in aqueous and binary aqueous media [13]. Adiabatic compressibility, apparent molal volume, apparent molal compressibility and solvation number of substituted azomethine drugs are reported[14]. The physico-chemical behavior for pure liquid components and their mixtures is studied on the basis of acoustic and thermodynamic properties[15]. Ultrasonic velocity and density have measured for non- aqueous solution of the ligands in DMSO solvent at 306K [16]. The acoustical properties of 1-(2’-hydroxy-5’ bromophenyl)-3-(4’-chlorophenyl)-1, 3 pronandione in dioxane-water mixture and also in different percentage of dioxane are reported[17].The ultrasonic velocity measurements of substituted hydrazone in 70% (DMF+water) solvents in different concentration is studied[18].Ultrasonic study is carried out for substituted 2, 3-dihydroquinazolin-4(1H)-ones in 70% DMF-Water at temperature 303K[19]. Molecular interaction of amide with aliphatic amine in benzene at different temperatures is reported[20]. Ultrasonic velocity and density measurements are done for levofloxacin, hemihydrate, tacrolimus, monohydrate and