Clinical Article POLYHERBAL FORMULATION AND ITS ROLE IN ALLEVIATING SIGNS OF DIARRHOEA IN BROILER BIRDS Mhase Prashant Patilba 1 , Anurag Borthakur 2 , Vikas Yadav 2 , K. Ravikanth 2 and Shivi Maini 2 1 Assistant Professor, Dept. of Veterinary Microbiology, Krantisinha Nana Patil College of Veterinary Science, Shirwal, Maharashtra-412801 2 Research and Development (R&D), Ayurvet Limited, Baddi, Himachal Pradesh E-mail: clinical@ayurvet.in (*Corresponding Author) Abstract: A total of 120 broiler birds were taken for the purpose of study and allotted into four different groups having 30 birds in each. Group T0 was kept as negative control. Group T1 was kept as positive control and challenged with E.coli on 8 th day and maintained on non medicated feed. Group T2 was treated with Salcochek at the rate of 500 g/tonne of feed (Prophylactic dose) with concomitant challenge with E.coli on 8 th day. Group T3 was treated with Salcochek at the rate of 1000g/tonne of feed (Therapeutic dose) with concomitant challenge with E.coli on 8 th day. Parameters viz. performance traits, clinical symptoms, mortality, TVC of E.coli in faecal samples, haemagglutination inhibition titre, gross and histopathological changes were evaluated. Results revealed that there was significant improvement in the mean weekly body weight and mean weight gain in the Salcochek (M/S Ayurvet) treated groups T2 and T3 as compared to the positive control group T0. Mortality % was significantly less in the Salcochek treated groups as compared to control group. Total viable E.coli count in faeces was also significantly reduced in the Salcochek treated groups as compared to control group. The Hemagglutination inhibition titre was significantly higher in the Salcochek treated groups as compared to control group. Thus, it can be inferred that Salcochek is highly effective in alleviating symptoms of diarrhea and promote growth in birds. Keywords: Body weight, Hemagglutination Inhibiton Titre, TVC, Diarrhoea. INTRODUCTION Enteric diseases are one of the most important problems in the poultry industry because of high economic losses due to decreased weight gain, increased mortality rates, worse feed conversion ratio, greater medication costs, and increased risk of contamination of poultry products for human consumption (Timbermont et al., 2011). Colibacillosis is one of the most important diseases threatening the poultry industry. (Ibrahim 1998, Ewers 2005, Ayoub 2007). Antimicrobial agents are used extremely in order to reduce the great losses caused by Escherichia coli infections in poultry industry (Talebiyan et al., 2014). However, there are International Journal of Science, Environment ISSN 2278-3687 (O) and Technology, Vol. 6, No 2, 2017, 1430 – 1437 2277-663X (P) Received Mar 6, 2017 * Published Apr 2, 2017 * www.ijset.net