JAGS 51:356–363, 2003
© 2003 by the American Geriatrics Society 0002-8614/03/$15.00
Visual Risk Factors for Hip Fracture in Older People
Rebecca Q. Ivers, B Optom, MPH, PhD,* Robert G. Cumming, MBBS, MPH, PhD,
†
Paul Mitchell, MD, PhD, FRACO,
‡
Judy M. Simpson, PhD, CStat,
†
and
Anthony J. Peduto, MB BS, FRANZCR
§
OBJECTIVES: To determine the association between
poor vision and risk of hip fracture in the Blue Mountains
Eye Study.
DESIGN: Prospective population-based cohort study.
SETTING: Two post code areas in the Blue Mountains,
west of Sydney, Australia.
PARTICIPANTS: Three thousand six hundred fifty-four
community-dwelling Australians aged 49 and older.
MEASUREMENTS: At baseline, subjects had an exten-
sive eye examination, including refraction, contrast sensi-
tivity and visual field testing, photographs of the lens and
retina, and an interview. Hip fractures during the 5-year
follow-up were identified by self-report and review of
medical records and were radiologically confirmed.
RESULTS: For 2-year follow-up (17 hip fractures), the
adjusted hazard ratio (HR) for risk of hip fracture in
those with corrected visual acuity worse than 20/60 was
8.4 (95% confidence interval (CI) = 1.5–48.5, popula-
tion attributable risk (PAR) = 27%); for presence of
posterior subcapsular cataract, the adjusted HR was 5.0
(95% CI = 1.1–23.0, PAR = 24%); and for visual field
loss, the adjusted HR was 5.5 (95% CI = 1.0–29.8,
PAR = 55%). In those aged 75 and older, visual acuity
worse than 20/60 gave an adjusted HR of 40.6 (95%
CI = 5.6–292.5, PAR = 49%). Visual impairment of
any type did not predict risk of hip fracture after a 2-
year follow-up.
CONCLUSION: Visual impairment is strongly associated
with risk of hip fracture in the next 2 years but not over a
longer period of time. J Am Geriatr Soc 51:356–363,
2003.
Key words: hip fracture; visual impairment; survival anal-
ysis; cohort
oor vision has long been recognized as a potential risk
factor for hip fracture in older people.
1–7
Visual im-
pairment occurs increasingly frequently as people age.
8,9
A
high proportion may be reversible by improving spectacle
correction
9
or by cataract surgery. Finding modifiable risk
factors for hip fracture is important, because hip fracture
incidence is increasing rapidly as the population ages.
10
The Blue Mountains Eye Study systematically mea-
sured and graded visual function and eye disease in an
older community-dwelling population. Subjects have now
been followed for an average 5.1 years. This study pro-
vides a good opportunity to carefully examine the associa-
tions between poor vision and hip fracture in an older
population. Because previous longitudinal studies have
had conflicting results and different lengths of follow-
up,
2,5,6
the aim of this study was to examine the associa-
tions between visual impairment and hip fracture after dif-
fering follow-up periods.
METHODS
Selection of Study Subjects
The Blue Mountains Eye Study is a population-based survey
of vision and common eye diseases in the Blue Mountains,
Australia. Details of the survey methods and procedures
have been described previously.
11–13
All noninstitutional-
ized residents aged 49 and older were identified in a cen-
sus. Of 4,433 eligible residents, 3,654 (82.4%) attended
the eye examination.
Baseline Assessment
Visual acuity was recorded with current glasses and after
subjective refraction using a LOGMAR chart.
9
Contrast
sensitivity was measured after refraction for subjects in the
first post code area using the Vectorvision CSV-1000 chart
(Vectorvision, Inc., Dayton, OH).
14
Visual fields were as-
sessed using the Humphrey 76 point 30° suprathreshold
screening test (Humphrey Instruments, Inc., San Leandro,
From the *Institute for International Health,
†
School of Public Health,
‡
Department of Ophthalmology, University of Sydney, Sydney, Australia;
and
§
Department of Radiology, Westmead Hospital, Westmead, Australia.
This study was supported by the Australian National Health and Medical
Research Council (NHMRC) and the Save Sight Institute, University of
Sydney. R. Q. Ivers was supported by a NHMRC (Public Health)
Research Scholarship.
Address correspondence to Dr. Rebecca Q. Ivers, Institute for International
Health, University of Sydney, PO Box 576, Newtown NSW 2042, Australia.
E-mail: rivers@iih.usyd.edu.au
P