macrophage fusion marker CD44. Neovascularization was detected within cellular lobules. Serum tests were normal. Clini- cal significance of vascular extension must be further clarified. No recurrence has occurred after 1 year. VASCULAR MALFORMATION ASSOCIATED WITH NUMEROUS PHLEBOLITHS: A CASE OF DIFFICULT DIAGNOSIS. HENRIQUE BEMFICA DE FARIA FREITAS, LUCIANA FONSECA, T  ULIO NAVARRO, GIOVANNA RIBEIRO SOUTO, HERM  INIA MARQUES CAPISTRANO, PAULO EDUARDO ALENCAR DE SOUZA and, SORAYA DE MATTOS CAMARGO GROSSMANN A 65-year-old man was referred to our service presenting with an atypical radiograph. During the anamnesis, no significant history was reported. In the intraoral exam, a blue-colored tumor with imprecise borders and irregular surface that was easily com- pressible and located in the basal regions, dorsum, and lingual belly of the left side was observed. Panoramic radiographic was performed again and revealed multiple ovoid and rounded areas, radiopaque, and well delineated on the left side, with an extraoss- eous location. A cystlike, unilocular, radiolucent defect was observed in the mandible. The diagnostic hypotheses included vascular malformation associated with phlebolith, infectious dis- eases associated with metastatic calcifications, and bone dis- eases. The test for a vascular lesion was performed. The diagnosis was vascular malformation associated with numerous phleboliths. The patient was referred to a hospital. The patient is under follow-up care and has experienced an increase in the number of phleboliths (after tooth extraction). RESECTION OF A LARGE AMELOBLAS- TOMA: A CASE REPORT. AMANDA LIMA DE OLIVEIRA, ELIZABETH GOMES DA COSTA, VALBER BARBOSA MARTINS, MARCELO VINICIUS OLIVEIRA, TATIANA NAYARA LIB  ORIO KIMURA, DIRCEU VIRGOLINO DE OLIVEIRA and, GUSTAVO CAVALCANTI DE ALBUQUERQUE Ameloblastoma is an odontogenic tumor that accounts for 1% of all facial tumors, is characterized by slow and painless growth, and is often diagnosed due to local volume increase or by routine radiography. A 34-year-old female patient attended the surgery service, reporting pain, dysphagia, dysphonia, and increased right hemiface volume for 10 years. Clinical examina- tion revealed a large bulge in the right mandibular region, with firm consistency and palpation. Oral and lingual bulging caused tongue detachment, dental dislocation, and trauma in the lesion. Computed tomography revealed multilocular areas, bone expan- sion, and extension of the lesion to the contralateral molar region. An incisional biopsy was performed, which was diagnosed as a multicystic ameloblastoma with a plexiform pattern. The patient underwent immediate reconstruction of the area, using a custom- ized acrylic resin prosthesis with a reconstruction plate 2.4. The patient is currently in the postoperative follow-up period, free of pain and rehabilitated with a total prosthesis. EXTENSIVE ULCERATIONS ASSOCIATED WITH THE USE OF MYCOPHENOLATE MOFETIL IN A PATIENT WITH HISTORY OF RENAL TRANSPLANT. JEFFERSON DA ROCHA TENORIO, NATH  ALIA TUANY DUARTE, MARINA MAU  ES TUMA, ROSANA SAINT CLAIR, KAREM L  OPEZ ORTEGA and, MARINA GALLOTTINI A 54-year-old white female patient presented with bilateral angular cheilitis and several painful ulcerated oral lesions, 11 years after kidney transplantation. The lesions affected the buccal mucosa, the soft palate, and dorsum of the tongue for 8 months. Her current immunosuppressive regimen includes myco- phenolate mofetil, tacrolimus, and prednisone. Periodic acid- Schiff (PAS) exfoliative cytology was positive for Candida spe- cies. An incisional biopsy was performed on the tongue lesion and the histopathologic examination revealed intense mixed inflammatory infiltrate in the connective tissue. Serologic tests excluded cytomegalovirus and herpes simplex infection. Thus, the diagnosis of oral candidiasis and ulcers associated with mycophenolate mofetil was established. Local therapy with anti- fungal and corticosteroid agents healed the lesions in buccal mucosa and soft palate. The tongue lesion did not respond to therapy. Buccal mucosa lesions recurred after a follow-up period of 1 month. The patient was referred to the nephrologist to evalu- ate for the possibility of changing the immunosuppressive thera- peutic regimen. MANAGEMENT OF PATIENTS WITH CAN- CER USING ANTIRESORPTIVE AND ANTI- ANGIOGENIC MEDICATIONS. JULIANA L SCHUSSEL, VITOR HUGO C FERREIRA, ARISTILIA P T KEMP, JOANA VENDRUSCOLO, ROBERTA T STRAMANDINOLI-ZANICOTTI and, LAURINDO M SASSI The increasing success of antiresorptive and antiangiogenic drugs in cancer treatment has significantly increased the risks of medication-related osteonecrosis of the jaw. In addition to bisphosphonates, monoclonal antibodies have often been associ- ated with this serious complication. The objective is to report the experience of the creation of an outpatient clinic for the treat- ment and prevention of osteonecrosis of the jaws at a public ref- erence hospital in oncology in the south of Brazil. Our experience has shown that most patients do not receive funda- mental guidelines regarding the contraindications of dental treat- ment in the use of these medications. Most patients are at high risk for the development of osteonecrosis such as generalized periodontal disease, decayed teeth, and presence of residual roots. In general, the patients have metastatic disease with a reserved prognosis and each case should be evaluated individu- ally with regard to the preventive or curative management for the disease. SURGICAL MANAGEMENT OF MANDIBU- LAR ODONTOGENIC MYXOMA: A CASE REPORT. FELIPE IGNACIO FUENTES Z  U e NIGA, LUIS MART  IN CASTRO HERRERA, RODRIGO ANDR  ES GUTI  ERREZ D  IAZ, MAXIMILIANO ANDR  ES MU e NOZ REPPETO and, ANA LUISA ALARC  ON ARRATIA Odontogenic myxoma is a locally aggressive benign odonto- genic tumor that mainly affects women. It occurs commonly in the mandible, being asymptomatic and slow growing. A male patient, 52 years old, was diagnosed with odontogenic myxoma. He presented with a painless swelling in the right ABSTRACTS OOOO e30 January 2020