ISSN 1070-3632, Russian Journal of General Chemistry, 2012, Vol. 82, No. 3, pp. 413–416. © Pleiades Publishing, Ltd., 2012. Original Russian Text © E.A. Dikusar, V.I. Potkin, D.A. Rudakov, T.D. Zvereva, S.K. Petkevich, M.M. Ogorodnikova, A.P. Yuvchenko, M.P. Bei, 2012, published in Zhurnal Obshchei Khimii, 2012, Vol. 82, No. 3, pp. 420–423. 413 Synthesis of o(m)-Carborane-Containing Azomethines E. A. Dikusar a,b , V. I. Potkin a , D. A. Rudakov a , T. D. Zvereva a , S. K. Petkevich a , M. M. Ogorodnikova a , A. P. Yuvchenko b , and M. P. Bei b a Institute of Physical Organic Chemistry of National Academy of Sciences of Belarus, ul. Surganova 13, Minsk, 220072 Belarus e-mail: dikusar@ifoch.bas-net.by b Institute of Chemistry of New Materials of National Academy of Sciences of Belarus, Minsk, Belarus Received January 18, 2011 Abstract—A method of preparative synthesis of o(m)-carborane-containing azomethines via the condensation of о(m)-carboranyl-С-methylene-4-formylbenzoates with aliphatic, cycloaliphatic, and aromatic amines was developed. Previously we have reported on the synthesis of o(m)-carborane-containing Schiff bases via the con- densation of vanillin esters of o(m)-carborane-C-car- boxylic acid and vanillin with amines [1–4]. The car- borane nitrogen-containing derivatives are of interest for research in the field of the boron neutron capture DOI: 10.1134/S1070363212030085 IIIа, IIIb CHO H 2 NR IVа−IVz', Vа−Vz' C(O)OCH 2 CB 10 H 10 CH-o(m) C C(O)OCH 2 CB 10 H 10 CH-o(m) H N R o(m)-HCB 10 H 10 CCH 2 OH 4-HC(O)C 6 H 4 C(O)Cl, Py −Py HCl Iа, Ib IVy', IVz', Vy', Vz' HC N C(O)CB 10 H 10 CH-o(m) 2 IVx', Vx' HC N(CH 2 ) 3 C(O)CB 10 H 10 CH-o(m) 2 IVy, Vy Me N O H Iа, IIIа, IVа– IVz' are о-carborane derivatives; Ib, IIIb, Vа–Vz' are m-carborane derivatives; IV, V: R = n-C 16 H 33 (a), n- C 18 H 37 (b), cyclo-С 6 H 11 (c), СH(1-Ad)Me (d), L-CH(CHMe 2 )CO 2 Me (e), L-CH(CHCH 2 Me 2 )CO 2 Me (f), L-CH(CHMeEt) CO 2 Me (g), L-CH(CH 2 Ph)CO 2 Me (h), 4-MeC 6 H 4 (i), 2-biphenyl (j), 4-biphenyl (k), 1-naphthyl (l), 2-naphthyl (m), 3- BrC 6 H 4 (n), 4-BrC 6 H 4 (o), 4-IC 6 H 4 (p), 1-bromo-2-naphthyl (q), 2-hydroxyphenyl (r), 4-phenoxyphenyl (s), 4-EtC(O)C 6 H 4 (t), 3-HO 2 CC 6 H 4 (u), 4-HO 2 CC 6 H 4 (v), 4-EtO 2 CC 6 H 4 (w), 4-BuO 2 CC 6 H 4 (x); IVx', Vx' are 1,6-hexamethylene diamine derivatives; IVy', IVz' , Vy', Vz' are 1,3- and 1,4-phenylene diamine derivatives. therapy of the tumor diseases, radionuclide diagnostics and therapy [5, 6]. In this work we describe the method of preparative synthesis of new o(m)-carborane azomethines IVa– IVz' and Va–IVz' by the condensation of o(m)-