Research Article RiskofSelectedFetalAdversePregnancyOutcomesatAdvanced MaternalAge:ARetrospectiveCohortStudyinDebreMarkos ReferralHospital,NorthwestEthiopia BikilaTeferaDebelo , 1 MelakuHunieAsratie , 2 andAbaynehAkliluSolomon 3 1 Department of Midwifery, College of Medicine and Health Science, Ambo University, Ambo, Ethiopia 2 Department of Women’s and Family Health, School of Midwifery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia 3 Department of Clinical Midwifery, School of Midwifery, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Correspondence should be addressed to Bikila Tefera Debelo; werkitef@gmail.com Received 22 June 2020; Revised 3 August 2020; Accepted 7 December 2020; Published 24 December 2020 Academic Editor: Curt W. Burger Copyright © 2020 Bikila Tefera Debelo et al. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Pregnancy at an advanced maternal age is defined as pregnancy at 35 years or older. Today, women postpone pregnancy due to different socioeconomic and personal reasons. However, there was limited evidence on fetal adverse outcomes’ association with pregnancy at an advanced maternal age in Ethiopia and particularly in the study area. is study was aimed at assessing the effect of pregnancy at an advanced age on selected neonatal adverse pregnancy outcomes in Debre Markos Referral Hospital, Ethiopia, 2019. Methods. Institution-based retrospective cohort study was conducted on 303 exposed (35 years and older) and 604 nonexposed (20–34 years old) immediate postpartum women who delivered at Debre Markos Referral Hospital after 28 weeks of gestation. All exposed women who fulfilled the inclusion criteria were sampled, and systematic random sampling was employed for those in the nonexposed group. e data were collected from 1st of July to 30th of December, 2019, by face-to-face interview and extraction from maternal chart using a structured questionnaire and data extraction checklist, respectively. Binary logistic regression (bivariate and multivariable) model was fitted, and wealth index was analyzed by principal component analysis. Adjusted relative risk with respect to 95% confidence interval was employed for the strength and directions of association between advanced maternal age and selected adverse pregnancy outcomes, respectively. P-value of <0.05 was used to declare statistical significance. Results. e incidence of adverse neonatal outcomes including stillbirth, preterm birth, and low birth weight in the advanced maternal age group was 13.2%, 19.8%, and 16.5%, respectively. e incidence of stillbirth, preterm birth, and low birth weight in the nonexposed group was 3.1%, 8.4%, and 12.4%, respectively. e advanced maternal age group had three times the risk of stillbirth compared with the nonexposed group (ARR=3.14 95% CI (1.30–7.00)). e advanced maternal age group had 2.66 times the risk of delivering preterm fetus (ARR=2.66 95% CI (1.81–3.77)) compared with the younger counterparts. Low birth weight was not significantly associated with pregnancy at an advanced maternal age. Conclusion. Fetal adverse outcomes including stillbirth and preterm birth were significantly associated with pregnancy at an advanced maternal age. 1.Background Advanced maternal age (AMA) is defined as pregnancy at a maternal age of 35 years or older [1]. AMA pregnancy varies across countries, from 33.4% in Norway to 11.4% in Taiwan [2, 3]. e proportion of pregnancy at AMA in three dif- ferent continents, Latin America, Middle East Asia, and Africa, is 12.3% [2]. Different reasons for postponing pregnancy were de- scribed by different studies. Occupational and socioeco- nomic, personal and marriage problems, childbearing desire and conception issues, and infertility were among the rea- sons for late-age pregnancy [4]. Pregnancy at AMA is associated with different adverse neonatal outcomes; however, there are contradicting ideas about those adverse outcomes. Pregnancy at AMA is Hindawi Obstetrics and Gynecology International Volume 2020, Article ID 1875683, 7 pages https://doi.org/10.1155/2020/1875683