How to Cite: Amneenah, A. M., Elzahaf, R. A., & Shahat, F. I. (2022). Comparison of diagnostic accuracy of transcutaneous bilirubin at different sites with serum total bilirubin measurement in preterm neonate. International Journal of Health Sciences, 6(S3), 8232– 8240. https://doi.org/10.53730/ijhs.v6nS3.7796 International Journal of Health Sciences ISSN 2550-6978 E-ISSN 2550-696X © 2022. Manuscript submitted: 27 March 2022, Manuscript revised: 18 April 2022, Accepted for publication: 9 May 2022 8232 Comparison of diagnostic accuracy of transcutaneous bilirubin at different sites with serum total bilirubin measurement in preterm neonate Abdullatif Mohammed Amneenah Associate Professor and Head of Pediatrics Departments-Faculty of Medicine- University of Derna, Consultant Pediatrician, Head of Pediatrics Departments- Al Wahda Teaching Hospital (Derna), Libya *Corresponding author email: aemnaina@gmail.com Raga A. Elzahaf Associate Professor Department of Public Health College of Medical Technology – Derna-Libya MENA Research Group -Libya Fayiza Ibrahim Shahat Lecturer at Faculty of medicine –University of Derna, Consultant Pediatrician at Al Wahda Teaching Hospital (Derna), Libya Abstract---Background: Transcutaneous bilirubin measurement (TcB) is widely used in term babies, but its effectiveness as well as the suitable site for (TcB) measurement in preterm babies still debated. Aim and Objective: To compare the diagnostic accuracy of different transcutaneous bilirubin sites with serum total bilirubin measurement in preterm neonate. Methods: This prospective comparative study was carried out in special care baby unit at Alwahda teaching hospital-Derna-Libya. (102) preterm infants (gestational age less than 37 weeks) in whom clinical jaundice was significant mandating TSB measurement were included in the study. Study subjects who met the inclusion criteria were chosen consecutively. All the measurements were carried out within first postnatal week. Transcutaneous bilirubin was measured from four sites: forehead, sternum, abdomen and interscapular region and within 30 min of TSB measurement. Results: Correlation coefficients of transcutaneous bilirubin measured from forehead, sternum, abdomen and interscapular sites were 0.69, 0.70, 0.67 and 0.69 respectively. TcB measured from all the four sites correlated significantly with serum bilirubin (p < 0.001), but the correlation was best at abdominal site. Conclusions: Transcutaneous bilirubin