gender. These results demonstrate that the life course ante- cedents, especially SES, of healthy aging are distinct for men and women. Interventions should prioritize reducing early- life exposure to socioeconomic disadvantage, especially for women. Given the gendered differences in the mediating effects, midlife interventions can be tailored for men and women. OLDER AMERICANS WITH DISABILITY ARE VULNERABLE TO ECONOMIC AND FOOD INSECURITY DURING COVID-19 Shinae Choi, 1 Eun Ha Namkung, 2 and Deborah Carr, 3 1. The University of Alabama, Tuscaloosa, Alabama, United States, 2. Korea Institute for Health and Social Affairs, Sejong, Ch'ungch'ong-namdo, Republic of Korea, 3. Boston University, Boston, Massachusetts, United States This study investigated whether older Americans with physical disability were vulnerable to three types of eco- nomic insecurity (diffculty paying regular bills, diffculty paying medical bills, income loss) and two types of food in- security (economic obstacles, logistical obstacles) during the early months of the COVID-19 pandemic. We evaluated the extent to which associations are moderated by three personal characteristics (age, sex, race/ethnicity) and two pandemic- specifc risk factors (job loss, COVID-19 diagnosis). Data were from a random 25 percent subsample of the Health and Retirement Study participants who completed a COVID-19 module administered in 2020. Our analytic sample included 3,166 adults aged 51 and older. We estimated logistic re- gression models to document the odds of experiencing each hardship. Persons with three or more functional limitations reported signifcantly higher odds of both types of food in- security, and diffculty paying regular and medical bills, rela- tive to those with no limitations. After controlling for health conditions, effects were no longer signifcant for paying med- ical bills, and attenuated yet remained statistically signifcant for other outcomes. Patterns did not differ signifcantly on the basis of the moderator variables. Older adults with more functional limitations are vulnerable to economic and food insecurity during the pandemic, potentially exacerbating the physical and emotional health threats imposed by the pan- demic. Our fndings reveal an urgent need to promote pol- icies and procedures to protect older adults with disability from economic and food insecurity. Supports for older adults with disability should focus on logistical as well as fnancial support for ensuring food security. TOWARD A MULTIDIMENSIONAL UNDERSTANDING OF LATER LIFE DISABILITY: A LATENT PROFILE ANALYSIS Natasha Peterson, 1 Jeongeun Lee, 2 and Eva Kahana, 3 1. Iowa State University, Iowa State University, Iowa, United States, 2. Iowa State University, Ames, Iowa, United States, 3. Case Western Reserve University, Cleveland, Ohio, United States Disability is diffcult to defne succinctly. Current litera- ture on disability has primarily focused on physical func- tional limitations. However, relying on a single dimension or index cannot accurately represent disability as the experi- ence of disability is nuanced and complex. To address these gaps, this study aims to understand the multidimensional nature of disability among retired, community-dwelling older adults. Using a sample of 414 older adults between the ages of 72 and 106 years (M=84.84, SD=4.56), latent profle analysis was employed to identify classes based on fve in- dicators of disability across three domains. The fve indica- tors of disability included diffculties with activities of daily living (ADLs), cognitive impairment, physical impairment, sensory impairment, and participation restrictions. Three classes were found to represent the data best. The most fa- vorable and highly functioning group comprised the highest number of participants (n=242, 59.5%). The next group, class 2 (n=157, 37.9%), was characterized by high physical impairment and ADL-diffculty. The smallest group, class 3 (n=15, 3.6%), had the highest ADL-diffculty and partici- pation restrictions but drastically lower cognitive and sen- sory impairment. Multinomial logistic regression revealed that class membership was related to sociodemographic characteristics. Finally, class membership predicted several mental health outcomes such as depressive symptoms, posi- tive affect, and life satisfaction in the expected direction. If supported by future work, these fndings could inform prac- titioners in developing more specifc interventions relevant to older adults based on their disability profles. Understanding various combinations of disablement has potential implica- tions for services and interventions to be tailored to individ- uals’ distinct disability-related needs. Session 2270 (Symposium) NEW BRAIN AGING CENTER Chair: Feng Lin Co-Chair: Yeates Conwell Discussant: Janine Simmons Evidence indicates an association between emotional well-being (EWB) and underlying brain processes, and that those processes change with both normal and pathological brain aging. However, the nature of these associations, the mechanisms by which EWB and its component domains change with brain aging, and how those changes may be associated with common neuropathologies like Alzheimer’s disease and related dementias (ADRD), are largely unex- plored. The NIA-funded Network for Emotional Well- being and Brain Aging (NEW Brain Aging) has the goal of developing a nationwide community of investigators dedi- cated to research that identifes and tests mechanisms by which brain aging infuences EWB and how EWB may impact risk for and progression of ADRD. Synthesizing human and animal literature, our premise is that relationships between EWB and ADRD are bidirectional – normal and pathological changes in aging brain infuence EWB and EWB contributes to brain health and illness, such as ADRD. NEW Brain Aging will identify and coalesce resources for interested investiga- tors and provide pilot funding opportunities to stimulate research and development of the feld. Component presenta- tions of this symposium will include (1) an overview by Dr. Robert Kaplan of the current state of research on EWB; (2) the role of animal studies (Kuan Hong Wang) and (3) human subjects research (Feng Vankee Lin) in EWB and aging; and (4) design of NEW Brain Aging and resources it will provide 202 Innovation in Aging, 2021, Vol. 5, No. S1 Downloaded from https://academic.oup.com/innovateage/article/5/Supplement_1/202/6465509 by guest on 04 June 2022